Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder.
Mehta S, Peterson H, Ye J, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Arora J, Tokoglu F, Yip S, Hahn C, Lacadie C, Greene A, Jeon S, Constable R, Barry D, Redeker N, Yaggi H, Scheinost D, Weintraub E. Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder. Radiology 2024, 313: e240514. PMID: 39656127, DOI: 10.1148/radiol.240514.Peer-Reviewed Original ResearchConceptsHealthy control participantsRight medial temporal lobeOpioid use disorderFunctional brain alterationsMedial temporal lobeOpioid use disorder groupFunctional connectivityUse disorderControl participantsBrain alterationsIntrinsic resting-state functional connectivityTemporal lobeMedial prefrontal cortex volumesVoxel-wise linear regressionT1-weighted MRIResting-state functional connectivityFamily-wise error correctionPrefrontal cortex volumeResting-state functional MRIIncreased functional connectivityIntrinsic connectivity distributionFunctional MRI studiesFemale participantsRegional brain volumesAssess group differencesInvestigating Brain State Engagement Variability in Individuals With Opioid Use Disorder Using Naturalistic and Task-Based fMRI Data
Ye J, Mehta S, Peterson H, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Yip S, Tokoglu F, Arora J, Constable R, Barry D, Redeker N, Yaggi H, Scheinost D. Investigating Brain State Engagement Variability in Individuals With Opioid Use Disorder Using Naturalistic and Task-Based fMRI Data. Biological Psychiatry 2024, 95: s6. DOI: 10.1016/j.biopsych.2024.02.022.Peer-Reviewed Original ResearchExperiences of Stigma and Discrimination Compounded by Intersecting Identities among Individuals Receiving Medication for Opioid Use Disorder.
Nwanaji-Enwerem U, Redeker N, O'Connell M, Barry D, Iheanacho T, Knobf T, Scheinost D, Wang K, Yaggi K, Sadler L. Experiences of Stigma and Discrimination Compounded by Intersecting Identities among Individuals Receiving Medication for Opioid Use Disorder. Journal Of Health Care For The Poor And Underserved 2024, 35: 94-115. PMID: 38661862, DOI: 10.1353/hpu.2024.a919810.Peer-Reviewed Original ResearchOpioid use disorderExperiences of stigmaIndividuals experience stigmaMarginalized social positionsIdentity of peopleUse disorderIntersectional identitiesMarginalized identitiesSupport interventionsSocial positionQualitative findingsStigmaNegative experiencesNortheast United StatesUnited StatesImprove outcomesIdentityTreatment centersMOUDIndividual vulnerabilityMedicationPeopleDiscriminationIndividuals