2022
A multidisciplinary approach to the diagnosis and management of Wilson disease: 2022 practice guidance on Wilson disease from the American Association for the Study of Liver Diseases
Schilsky ML, Roberts EA, Bronstein JM, Dhawan A, Hamilton JP, Rivard AM, Washington MK, Weiss KH, Zimbrean PC. A multidisciplinary approach to the diagnosis and management of Wilson disease: 2022 practice guidance on Wilson disease from the American Association for the Study of Liver Diseases. Hepatology 2022, Publish Ahead of Print PMID: 36151586, DOI: 10.1002/hep.32801.Peer-Reviewed Original ResearchA multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the American Association for the Study of Liver Diseases
Schilsky ML, Roberts EA, Bronstein JM, Dhawan A, Hamilton JP, Rivard AM, Washington MK, Weiss KH, Zimbrean PC. A multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the American Association for the Study of Liver Diseases. Hepatology 2022, 77: 1428-1455. PMID: 36152019, DOI: 10.1002/hep.32805.Peer-Reviewed Original Research
2020
P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Coskun A, Patel A, Wadhwa A, Apdik T, Tomlin R, Deng Y, Gonzalez-Peralta R, Schilsky M. P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.23.Peer-Reviewed Original ResearchMental health issuesWilson's diseaseHealth issuesSeverity of liverMental health QOLPhysical health QoLReview of imagingP-QOL scoresQuality of lifeFIB4 scoreAdult patientsRegistry studyNeurological assessmentPhysical health issuesChronic diseasesOutcome measuresPatientsNeurological diseasesWD patientsQoLAssess qualityDiseaseCirrhosisSignificant differencesScoresFRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life
Camarata M, Ala A, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Maciejewski K, Song X, Deng Y, Tomlin R, Apdik T, Coskun A, Schilsky M. FRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life. Journal Of Hepatology 2020, 73: s550-s551. DOI: 10.1016/s0168-8278(20)31573-7.Peer-Reviewed Original Research
2018
Dialysis: Medical and Psychological Considerations
Hussain F, Zimbrean P. Dialysis: Medical and Psychological Considerations. 2018, 91-102. DOI: 10.1007/978-3-319-94914-7_7.Peer-Reviewed Original ResearchEnd-stage renal diseaseChronic kidney diseaseStage 5 chronic kidney diseaseDiscontinuation of dialysisRenal replacement modalityAge-matched cohortDemand of dialysisRenal diseasePeritoneal dialysisReplacement modalityCenter hemodialysisKidney diseasePatient populationWorse outcomesSleep disordersGeneral populationMortality rateRelevant pharmacologyHome dialysisPsychiatric implicationsMedical considerationsPatientsDialysisIncreased ratesDiseasePsychiatric Aspects of Wilson Disease
Munjal S, Zimbrean P. Psychiatric Aspects of Wilson Disease. Clinical Gastroenterology 2018, 121-142. DOI: 10.1007/978-3-319-91527-2_7.Peer-Reviewed Original Research
2017
Psychiatric comorbidity in Wilson’s disease
Mura G, Zimbrean PC, Demelia L, Carta MG. Psychiatric comorbidity in Wilson’s disease. International Review Of Psychiatry 2017, 29: 445-462. PMID: 28681670, DOI: 10.1080/09540261.2017.1311845.Peer-Reviewed Original ResearchConceptsWilson's diseasePsychiatric disordersCase-control studyAutosomal recessive inherited disorderPubMed/MEDLINERare autosomal recessive inherited disorderBetter life expectancyRecessive inherited disorderPsychiatric comorbidityCase reportSpecific therapyAvailable treatmentsPsychiatric disturbancesHigh prevalenceMood disordersPsychiatric symptomsPsychiatric outcomesClinical monitoringTherapeutic issuesPsychosocial outcomesInherited disorderRelevant articlesDiseaseGoogle ScholarCareful evaluationChapter 11 Cognitive and psychiatric symptoms in Wilson disease
Zimbrean P, Seniów J. Chapter 11 Cognitive and psychiatric symptoms in Wilson disease. Handbook Of Clinical Neurology 2017, 142: 121-140. PMID: 28433097, DOI: 10.1016/b978-0-444-63625-6.00011-2.Peer-Reviewed Original ResearchConceptsWilson's diseaseClinical experienceAuthors' clinical experienceNonpharmacologic treatmentsGreat masqueraderIndividual patientsPsychiatric symptomsMood disturbanceCognitive symptomsPsychiatric pathologyCognitive deficitsDiseaseSymptomsExecutive functionImpairmentPatientsPrevalencePsychosisPathology
2015
Psychiatric and medical adverse events for kidney transplant recipients with lithium induced kidney disease
Zimbrean P, Formica R, Ash W, Lettieri D, Kulkarni S. Psychiatric and medical adverse events for kidney transplant recipients with lithium induced kidney disease. Journal Of Psychosomatic Research 2015, 78: 634. DOI: 10.1016/j.jpsychores.2015.03.148.Peer-Reviewed Original Research
2013
Psychiatric aspects of Wilson disease: a review
Zimbrean PC, Schilsky ML. Psychiatric aspects of Wilson disease: a review. General Hospital Psychiatry 2013, 36: 53-62. PMID: 24120023, DOI: 10.1016/j.genhosppsych.2013.08.007.Peer-Reviewed Original ResearchConceptsPsychiatric symptomsPsychiatric manifestationsWilson's diseasePsychiatric disordersPercent of patientsTime of diagnosisDiagnosis of WDCertain gene mutationsHepatic involvementNeurologic involvementClinical presentationPsychiatric presentationsCurrent evidencePsychiatric aspectsPubMed databaseWD patientsSymptomsDiseaseDiagnosisWD diagnosisGene mutationsAverage timePatientsManifestationsDisorders