Publications

2026

Tumour–brain crosstalk restrains cancer immunity via a sensory–sympathetic axis
Wei, H.K., Yu, C.D., Hu, B. et al. Tumour–brain crosstalk restrains cancer immunity via a sensory–sympathetic axis. Nature (2026). https://doi.org/10.1038/s41586-025-10028-8
Peer-Reviewed Original Research
Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life.
Landajuela A, Gomis Perez C, Bassereau P, Callan-Jones A, Karatekin E. Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life. Sci Adv 2026, 12: eadz7607. PMID: 41499510, DOI: 10.1126/sciadv.adz7607.
Peer-Reviewed Original Research

2025

Compartmentalized nutrient and hormone sensing in β-cells: the role of cilia
Hughes J, Merrins M. Compartmentalized nutrient and hormone sensing in β-cells: the role of cilia. Physiology 2025 PMID: 41432705, DOI: 10.1152/physiol.00042.2025.
Peer-Reviewed Original Research
Endothelial Rho kinase controls blood vessel integrity and angiogenesis
Lange M, Francis C, Furtado J, Granger J, Kim Y, Liao J, Akar F, Eichmann A. Endothelial Rho kinase controls blood vessel integrity and angiogenesis. Cardiovascular Research 2025, cvaf246. PMID: 41403023, DOI: 10.1093/cvr/cvaf246.
Peer-Reviewed Original Research
Concepts
Characterization of arteriovenous thrombus formation and propagation in a mouse arteriovenous fistula model
bai H, Li Z, Ho B, Cai Y, Hwa J, Dardik A. Characterization of arteriovenous thrombus formation and propagation in a mouse arteriovenous fistula model. Thrombosis And Haemostasis 2025 PMID: 41401940, DOI: 10.1055/a-2772-5837.
Peer-Reviewed Original Research
Concepts
Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition
Leitner B, Fosam A, Lee W, Zilinger K, Nakandakari S, Zhang X, Gaspar R, Zhu W, Perry C, Rabinowitz J, Perry R. Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2508707122. PMID: 41325517, PMCID: PMC12704748, DOI: 10.1073/pnas.2508707122.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
GARLH regulates neuroligin preference for excitatory versus inhibitory synapses
Yamasaki T, Konno K, Krueger-Burg D, Noam Y, Chaudhury N, Morimoto-Tomita M, Salm E, Watanabe M, Brose N, Tomita S. GARLH regulates neuroligin preference for excitatory versus inhibitory synapses. Journal Of Cell Biology 2025, 225: e202507190. PMID: 41329163, DOI: 10.1083/jcb.202507190.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Resolving the mysteries of brain clearance and immune surveillance
Kipnis J, Benveniste H, Eichmann A, Thomas J, Reich D, Lewis L, Tsai L, Drieu A, Bakker E, Kelley D, Lundgaard I, Mestre H, Zott B, Eide P, van Osch M, van Veluw S, Iliff J, Yang A, Santambrogio L, Da Mesquita S, Daneman R, Rustenhoven J, Goldman S, Nedergaard M. Resolving the mysteries of brain clearance and immune surveillance. Neuron 2025, 113: 3908-3923. PMID: 41289996, DOI: 10.1016/j.neuron.2025.10.036.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
ARMH2 is a cytosolic component of CatSper crucial for sperm function
De Rito C, Sassi G, Percudani R, Chung J. ARMH2 is a cytosolic component of CatSper crucial for sperm function. Nature Communications 2025, 16: 10243. PMID: 41271765, PMCID: PMC12638846, DOI: 10.1038/s41467-025-65952-0.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice.
Abe T, Xu S, Sugiura Y, Arima Y, Hayasaka T, Lee M, Ishimoto T, Araki Y, Ngurari S, Niu Z, Iijima N, Diano S, Toda C. Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice. Diabetes 2025, 74: 2390-2404. PMID: 41264848, DOI: 10.2337/db25-0106.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Turbulence drives arteriovenous remodeling: an experimentally validated multi-scale model of neointimal hyperplasia
Varsanik M, Thaxton C, Nguyen D, Pugar J, Dhara S, Li W, Nguyen N, Dardik A, Pocivavsek L. Turbulence drives arteriovenous remodeling: an experimentally validated multi-scale model of neointimal hyperplasia. Physics In Medicine And Biology 2025, 70: 235009. PMID: 41183446, DOI: 10.1088/1361-6560/ae1ac8.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
The prevalence of ENPP1 deficiency in humans with OPLL and the preclinical efficacy of ENPP1 enzyme therapy in OPLL mice.
Srivastava S*, Kato H*, von Kroge S*, Weise K, Stabach P, Lopez SG, O'Brien K, Lester ER, Kim H, Ishaq T, Dammen-Brower K, Schinke T, Kimura S, Miyahara J, Doi T, Oshima Y, Yarema KJ, Carpenter TO, Sabbagh Y, Tommasini SM, Ito N, Oheim R, Braddock DT. The prevalence of ENPP1 deficiency in humans with OPLL and the preclinical efficacy of ENPP1 enzyme therapy in OPLL mice. Journal of Bone and Mineral Research. 2025 PMID: 41251406, DOI: 10.1093/jbmr/zjaf168.
Peer-Reviewed Original Research
The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament
Srivastava S, Kato H, von Kroge S, Weise K, Stabach P, Lopez S, O’Brien K, Lester E, Kim H, Ishaq T, Dammen-Brower K, Schinke T, Kimura S, Miyahara J, Doi T, Oshima Y, Yarema K, Carpenter T, Sabbagh Y, Tommasini S, Ito N, Oheim R, Braddock D. The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament. Journal Of Bone And Mineral Research 2025, zjaf168. PMID: 41251406, DOI: 10.1093/jbmr/zjaf168.
Peer-Reviewed Original Research
Concepts
Pathophysiology of Atherosclerotic Carotid Disease
Ho B, Batarseh P, Dardik A. Pathophysiology of Atherosclerotic Carotid Disease. Seminars In Neurology 2025 PMID: 41248882, DOI: 10.1055/a-2735-9854.
Peer-Reviewed Original Research
Concepts
Interactions among tumor subtype, PPARγ expression, and adipose proliferation shape outcomes in breast cancer
Shah A, Liu K, Liu R, Ramshankar G, Perry C, Perry R. Interactions among tumor subtype, PPARγ expression, and adipose proliferation shape outcomes in breast cancer. Physiological Reports 2025, 13: e70649. PMID: 41236441, PMCID: PMC12617248, DOI: 10.14814/phy2.70649.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
How might intraluminal drug-delivery strategies be improved to enhance arteriovenous fistula maturation and patency?
George J, Rao A, Dardik A. How might intraluminal drug-delivery strategies be improved to enhance arteriovenous fistula maturation and patency? Expert Opinion On Drug Delivery 2025, ahead-of-print: 1-4. PMID: 41208053, DOI: 10.1080/17425247.2025.2588377.
Peer-Reviewed Original Research
Concepts
Gut Microbiota and Dietary Strategies for Age-Related Diseases
Prabhat Upadhyay*, Sudhir Kumar*, Hanish Singh Jayasingh Chellammal, Neha Sahu, Shivani Srivastava, Raj Kumar, and Amin Gasmi. Gut Microbiota and Dietary Strategies for Age-Related Diseases. Molecular Nutrition & Food Research. 2025; e70308. PMID: 41195914, DOI: 10.1002/mnfr.70308
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Gut Microbiota and Dietary Strategies for Age‐Related Diseases
Upadhyay P, Kumar S, Chellammal H, Sahu N, Srivastava S, Kumar R, Gasmi A. Gut Microbiota and Dietary Strategies for Age‐Related Diseases. Molecular Nutrition & Food Research 2025, 69: e70308. PMID: 41195914, DOI: 10.1002/mnfr.70308.
Peer-Reviewed Original Research
Concepts
Restoring compromised blood-retina-barrier integrity with Netrin-1 overexpression
Furtado J, Zapadka T, Park H, Boyé K, Demb J, Eichmann A. Restoring compromised blood-retina-barrier integrity with Netrin-1 overexpression. Cellular And Molecular Life Sciences 2025, 82: 389. PMID: 41196411, PMCID: PMC12592616, DOI: 10.1007/s00018-025-05903-6.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Chronic pulmonary LPS exposure in cystic fibrosis drives maladaptive pro-inflammatory hematopoietic stem and progenitor cells
Isler Mancuso R, Thompson E, Braga C, Oez H, Gudneppanavar R, Zhang P, Neves T, Krause W, Huang P, Murray T, Egan M, Bruscia E, Krause D. Chronic pulmonary LPS exposure in cystic fibrosis drives maladaptive pro-inflammatory hematopoietic stem and progenitor cells. Blood 2025, 146: 3175-3175. DOI: 10.1182/blood-2025-3175.
Peer-Reviewed Original Research
Concepts
Polyunsaturated fatty acids control lipid membrane dynamics and ferroptosis sensitivity in B-cell lymphoma
Leveille E, Bramson E, Robinson M, Perez C, Chahal O, Bertomeu T, Chatr-aryamontri A, Kothari S, Gupta K, Karatekin E, Xiao G, Lancaster G, Murphy A, Conrad M, Müschen M. Polyunsaturated fatty acids control lipid membrane dynamics and ferroptosis sensitivity in B-cell lymphoma. Blood 2025, 146: 5094-5094. DOI: 10.1182/blood-2025-5094.
Peer-Reviewed Original Research
Concepts
Altered Epithelial-Mesenchymal Progenitor States Lead to Matrix Deposition, Tissue Inflammation, and Transitional Epithelial State in Congenital Diaphragmatic Hernia
Rivero R, Edelstein S, Haynes C, Mizoguchi S, Wang N, Saltzman M, Stitelman D, Raredon M. Altered Epithelial-Mesenchymal Progenitor States Lead to Matrix Deposition, Tissue Inflammation, and Transitional Epithelial State in Congenital Diaphragmatic Hernia. Fetal And Pediatric Pathology 2025, 44: 551-572. PMID: 41246903, DOI: 10.1080/15513815.2025.2585371.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
The role of the ventromedial hypothalamus in glycemic responses
Zilinger K, Perry R. The role of the ventromedial hypothalamus in glycemic responses. Cell Metabolism 2025, 37: 2097-2098. PMID: 41192357, DOI: 10.1016/j.cmet.2025.10.004.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Optimal treatment of preclinical cardiovascular disease: a narrative review with a focus on carotid artery stenosis
Paraskevas K, Mikhailidis D, Myrcha P, AbuRahma A, Blecha M, Mansilha A, Blinc A, Heiss C, Sawicka A, Setacci C, Zeebregts C, Spinelli F, Stilo F, Witte M, Lanza G, Jug B, Hendiger W, Myrcha J, Taranta I, Goryn T, D’Oria M, Fernandes e Fernandes J, Reijnen M, di Lazzaro V, Lepidi S, Goudot G, Lal B, Jawien A, Lavie C, Mackevicius A, Baltrunas T, Głowiński J, Liapis C, Menyhei G, Secemsky E, Stanek A, Saba L, Balestrieri A, Ferreira J, Lanza J, Crupi D, Pitha J, Pecoraro F, Setacci F, Svetlikov A, Gurevich V, Silvestrini M, Pilato F, Schneider P, White C, Reiff T, Gargiulo M, Faggioli G, Chaturvedi S, Malas M, Perler B, Dardik A, Nicolaides A, Poredos P, Hicks C. Optimal treatment of preclinical cardiovascular disease: a narrative review with a focus on carotid artery stenosis. Seminars In Vascular Surgery 2025 DOI: 10.1053/j.semvascsurg.2025.11.003.
Peer-Reviewed Original Research
Concepts
A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia
Elliott S, Ready P, Wrinn C, Ma Q, Edward M, Niescier R, Escobar I, Sun J, Ganga A, McAtee C, Atiş İ, Koleske A, Bordey A, Breslow D. A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia. Science Advances 2025, 11: eaeb7238. PMID: 41160700, PMCID: PMC12571082, DOI: 10.1126/sciadv.aeb7238.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

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