Principles of Mechanosensing at the Membrane Interface
Bavi N, Nikolaev Y, Bavi O, Ridone P, Martinac A, Nakayama Y, Cox C, Martinac B. Principles of Mechanosensing at the Membrane Interface. Springer Series In Biophysics 2017, 19: 85-119. DOI: 10.1007/978-981-10-6244-5_4.Peer-Reviewed Original ResearchChannel mechanosensitivityTransbilayer pressure profileIon channel mechanosensitivitySpecific cellular responsesMechanosensitive ion channelsMolecular mechanosensorsCellular mechanotransductionIntracellular signalsPhysiological processesCellular responsesMechanosensory transducersLiving cellsExtracellular matrixIon channelsChannel conformationLipid bilayersMembrane interfaceMechanotransductionMechanosensitivityMechanical stimuliCellsCytoskeletonMechanosensorsLipidsConformationAdding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling
Friedrich O, Schneidereit D, Nikolaev Y, Nikolova-Krstevski V, Schürmann S, Wirth-Hücking A, Merten A, Fatkin D, Martinac B. Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling. Progress In Biophysics And Molecular Biology 2017, 130: 170-191. PMID: 28647645, DOI: 10.1016/j.pbiomolbio.2017.06.011.Peer-Reviewed Original ResearchConceptsFocal adhesion complexesCell-substrate junctionLive-cell imagingMechanosensitive ion channelsDirect mechanistic studiesAdhesion complexesCellular mechanotransductionMembrane junctionsIntracellular signalingMechanotransduction researchCellular stretchCellular modelIon channelsCellular levelCell membraneMechanotransductionIndividual cardiomyocytesBiomedical engineeringMechanical wall stressMembraneMechanistic studiesCellsStretch deviceCardiomyocytesElastomeric membrane