2004
Renal and intestinal transport defects in Slc26a6-null mice
Wang Z, Wang T, Petrovic S, Tuo B, Riederer B, Barone S, Lorenz JN, Seidler U, Aronson PS, Soleimani M. Renal and intestinal transport defects in Slc26a6-null mice. American Journal Of Physiology - Cell Physiology 2004, 288: c957-c965. PMID: 15574486, DOI: 10.1152/ajpcell.00505.2004.Peer-Reviewed Original ResearchConceptsWild-type miceProximal tubulesSlc26a6-null miceHCO3- secretionKidney proximal tubulesApical membrane ClNull miceBaseline rateNormal blood pressureCl-/formate exchangeBlood pressureKidney functionElectrolyte profileMucosal tissuesIntestinal physiologyUssing chambersSmall intestineMiceFluid absorptionNaCl absorptionStatistical significanceCl-/HCO3NaCl transportDuodenumTubules
2003
Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium
Coric T, Hernandez N, de la Rosa D, Shao D, Wang T, Canessa CM. Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium. AJP Gastrointestinal And Liver Physiology 2003, 286: g663-g670. PMID: 14630642, DOI: 10.1152/ajpgi.00364.2003.Peer-Reviewed Original ResearchMeSH KeywordsAldosteroneAnimalsAntibodies, BlockingAntibody SpecificityBlotting, NorthernCHO CellsColonCricetinaeDNA, ComplementaryEnzyme InductionEpithelial Sodium ChannelsEpitheliumFluorescent Antibody TechniqueImmediate-Early ProteinsIntestinal MucosaNuclear ProteinsPlasmidsProtein Serine-Threonine KinasesRatsRNA, MessengerSignal TransductionSodium ChannelsConceptsDistal colonGlucocorticoid-induced kinase 1Intestinal epitheliumConcentrations of aldosteroneSubunits of ENaCSodium channel activityExpression of ENaCRat intestinal epitheliumKinase 1Aldosterone levelsAldosterone-dependent mannerSingle doseSodium depletionChronic increaseDistal tubulesControl animalsAldosteroneAldosterone inductionRat intestineBasal conditionsColonSodium transportersEpitheliumSites of expressionSGK1