2015
Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression
Guo X, Li Z, Zhang C, Yi Z, Li H, Cao L, Yuan C, Hong W, Wu Z, Peng D, Chen J, Xia W, Zhao G, Wang F, Yu S, Cui D, Xu Y, Golam CM, Smith AK, Wang T, Fang Y. Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression. Journal Of Psychiatric Research 2015, 69: 1-6. PMID: 26343587, DOI: 10.1016/j.jpsychires.2015.07.011.Peer-Reviewed Original ResearchConceptsSubsyndromal symptomatic depressionPeripheral blood mononuclear cellsHan Chinese patientsSSD patientsMRNA expression levelsMDD patientsSymptomatic depressionChinese patientsBlood mononuclear cellsSingle nucleotide polymorphismsExpression levelsMononuclear cellsPatientsMRNA expressionCommon diseaseReal-time quantitative PCR studiesSignificant decreaseSignificant social dysfunctionSocial dysfunctionPCR studiesCandidate genesTranscript networksFunctional annotation toolMultiple single nucleotide polymorphismsQuantitative PCR studies
2003
Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium
Coric T, Hernandez N, de la Rosa D, Shao D, Wang T, Canessa CM. Expression of ENaC and serum- and glucocorticoid-induced kinase 1 in the rat intestinal epithelium. AJP Gastrointestinal And Liver Physiology 2003, 286: g663-g670. PMID: 14630642, DOI: 10.1152/ajpgi.00364.2003.Peer-Reviewed Original ResearchMeSH KeywordsAldosteroneAnimalsAntibodies, BlockingAntibody SpecificityBlotting, NorthernCHO CellsColonCricetinaeDNA, ComplementaryEnzyme InductionEpithelial Sodium ChannelsEpitheliumFluorescent Antibody TechniqueImmediate-Early ProteinsIntestinal MucosaNuclear ProteinsPlasmidsProtein Serine-Threonine KinasesRatsRNA, MessengerSignal TransductionSodium ChannelsConceptsDistal colonGlucocorticoid-induced kinase 1Intestinal epitheliumConcentrations of aldosteroneSubunits of ENaCSodium channel activityExpression of ENaCRat intestinal epitheliumKinase 1Aldosterone levelsAldosterone-dependent mannerSingle doseSodium depletionChronic increaseDistal tubulesControl animalsAldosteroneAldosterone inductionRat intestineBasal conditionsColonSodium transportersEpitheliumSites of expressionSGK1