Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule.
Wang T, Malnic G, Giebisch G, Chan Y. Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule. Journal Of Clinical Investigation 1993, 91: 2776-2784. PMID: 8390489, PMCID: PMC443344, DOI: 10.1172/jci116519.Peer-Reviewed Original ResearchConceptsLate distal tubuleBicarbonate absorptionDistal tubulesTubule segmentsBicarbonate transportH-ATPaseH-K-ATPase inhibitorsRate of bicarbonate absorptionEthyl-isopropylamilorideFluid absorptionNa(+)-H+ exchangeK(+)-H+ exchangeEarly distal tubuleBicarbonate transport mechanismDistal tubule segmentsRenal bicarbonate reabsorptionLow-K dietLuminal bicarbonate concentrationBicarbonate reabsorptionBicarbonate secretionBicarbonate concentrationH+ secretionMicroperfusion experimentsTubulesK diet