2023
The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine
Rajendran P, Hadaya J, Khalsa S, Yu C, Chang R, Shivkumar K. The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine. Seminars In Cell And Developmental Biology 2023, 156: 190-200. PMID: 36641366, PMCID: PMC10336178, DOI: 10.1016/j.semcdb.2023.01.001.Peer-Reviewed Original ResearchConceptsParasympathetic nervous systemNervous systemEvolutionary insightsGenetic diversityComparative biologySympathetic nervous systemParasympathetic dysfunctionVagal neuronsBlood pressureVagal efferentsAfferent innervationVagus nerveHeart diseaseCardiovascular functionCardiovascular diseaseHeart rateTherapeutic potentialCardiovascular physiologyDiseaseClinical medicineHeartBiologyDiversityInnervationNerve
2020
Vagal sensory neurons and gut-brain signaling
Yu CD, Xu QJ, Chang RB. Vagal sensory neurons and gut-brain signaling. Current Opinion In Neurobiology 2020, 62: 133-140. PMID: 32380360, PMCID: PMC7560965, DOI: 10.1016/j.conb.2020.03.006.Peer-Reviewed Original ResearchConceptsVagal sensory neuronsGut-brain signalingSensory neuronsGut-derived signalsTrans-synaptic tracingImmune controlVagus nerveImmunological disordersBrain pathwaysAnatomical basisNovel physiological functionCellular mechanismsActivity recordingsNeural activity recordingNeuronsRecent findingsNew gutPhysiological functionsGutGut systemSingle-cell genomic analysisSignalingAfferentsNervePsychological regulation