A proton current drives action potentials in genetically identified sour taste cells
Chang RB, Waters H, Liman ER. A proton current drives action potentials in genetically identified sour taste cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 22320-22325. PMID: 21098668, PMCID: PMC3009759, DOI: 10.1073/pnas.1013664107.Peer-Reviewed Original ResearchConceptsTaste cellsSour stimuliSour taste cellsAction potential firingSour taste transductionAcid stimuliGenetic ablation experimentsSuction electrode recordingsSour sensingSour cellsSubset of cellsAction potentialsPKD1L3 genesExpression of YFPResponsive cellsTaste cell membraneElectrode recordingsNumerous ion channelsTaste budsTaste transductionTargeted deletionSour transductionIon channels