2012
Deep sequencing the circadian and diurnal transcriptome of Drosophila brain
Hughes ME, Grant GR, Paquin C, Qian J, Nitabach MN. Deep sequencing the circadian and diurnal transcriptome of Drosophila brain. Genome Research 2012, 22: 1266-1281. PMID: 22472103, PMCID: PMC3396368, DOI: 10.1101/gr.128876.111.Peer-Reviewed Original ResearchMeSH KeywordsAlternative SplicingAnimalsBase SequenceBrainCircadian ClocksCircadian RhythmDrosophila melanogasterExonsGene Expression ProfilingMolecular Sequence AnnotationPhotoperiodRNA EditingRNA IsoformsRNA Splice SitesRNA, UntranslatedSequence AlignmentSequence Analysis, RNATranscription, GeneticTranscriptomeConceptsKey circadian genesRNA editingNoncoding RNAsCircadian genesDrosophila brainGenome-wide mapsEukaryotic circadian clocksCircadian transcriptional rhythmsSnoRNA host genesTranslational feedback loopsSmall nucleolar RNAsNovel splicing eventsAlternative splice isoformsDark diurnal cyclesFrequency of RNAPrevious microarray studyDiurnal transcriptomeDrosophila melanogaster brainTranscriptional rhythmsCircadian transcriptomeNcRNA expressionRibosomal biogenesisModENCODE consortiumSplicing eventsAlternative splicing
2011
Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells
Silver AC, Arjona A, Hughes ME, Nitabach MN, Fikrig E. Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells. Brain Behavior And Immunity 2011, 26: 407-413. PMID: 22019350, PMCID: PMC3336152, DOI: 10.1016/j.bbi.2011.10.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsARNTL Transcription FactorsB-LymphocytesCircadian RhythmCircadian Rhythm Signaling Peptides and ProteinsCLOCK ProteinsDendritic CellsDNA-Binding ProteinsGene ExpressionMacrophagesMiceNuclear Receptor Subfamily 1, Group D, Member 1Period Circadian ProteinsPhotoperiodSpleenTranscription FactorsConceptsMolecular clock mechanismClock genesClock mechanismGene expressionClock-controlled transcription factorsFunctional molecular clockAspects of physiologyConstant environmental conditionsMolecular clockTranscription factorsCircadian expressionB cellsEnvironmental conditionsLight-dark cycleMouse macrophagesDaily rhythmsGenesExpressionCellsDendritic cellsMurine spleenMammalsMacrophagesSplenic NK cellsImmune cellsInsect circadian clock outputs
Helfrich-Förster C, Nitabach MN, Holmes TC. Insect circadian clock outputs. Essays In Biochemistry 2011, 49: 87-101. PMID: 21819386, DOI: 10.1042/bse0490087.Peer-Reviewed Original ResearchConceptsClock neuronsDaily rhythmsCircadian clock outputBrain clockCellular clocksDrosophila fliesCircadian timekeeping systemCircadian outputEnvironmental cuesClock outputMigratory locustInsectsTimekeeping systemCircadian rhythmicitySubstantial similarityClockImpressive varietyButterfliesLocal environmentFliesClock circuitEntire lifeLocustTimekeeperPhysiology