2002
Correlation of myocardial p-(123)I-iodophenylpentadecanoic acid retention with (18)F-FDG accumulation during experimental low-flow ischemia.
Shi CQ, Young LH, Daher E, DiBella EV, Liu YH, Heller EN, Zoghbi S, Wackers FJ, Soufer R, Sinusas AJ. Correlation of myocardial p-(123)I-iodophenylpentadecanoic acid retention with (18)F-FDG accumulation during experimental low-flow ischemia. Journal Of Nuclear Medicine 2002, 43: 421-31. PMID: 11884504.Peer-Reviewed Original Research
1996
Glucose metabolism distal to a critical coronary stenosis in a canine model of low-flow myocardial ischemia.
McNulty PH, Sinusas AJ, Shi CQ, Dione D, Young LH, Cline GC, Shulman GI. Glucose metabolism distal to a critical coronary stenosis in a canine model of low-flow myocardial ischemia. Journal Of Clinical Investigation 1996, 98: 62-69. PMID: 8690805, PMCID: PMC507401, DOI: 10.1172/jci118778.Peer-Reviewed Original ResearchConceptsLow-flow ischemiaCoronary stenosisIschemic myocardiumIschemic regionLow-flow myocardial ischemiaCritical coronary stenosisExogenous glucoseOxidative substrateMyocardial ischemiaIntact dogsGlucose metabolismNonischemic regionsClinical observationsCanine modelGlucose utilizationIschemiaBiochemical measurementsMyocardial regionsRate of incorporationIntracellular metabolismTricarboxylic acid cycle fluxStenosisMyocardiumGlucoseGlucose-derived pyruvate
1995
Technetium-99m-nitroimidazole (BMS181321): a positive imaging agent for detecting myocardial ischemia.
Shi CQ, Sinusas AJ, Dione DP, Singer MJ, Young LH, Heller EN, Rinker BD, Wackers FJ, Zaret BL. Technetium-99m-nitroimidazole (BMS181321): a positive imaging agent for detecting myocardial ischemia. Journal Of Nuclear Medicine 1995, 36: 1078-86. PMID: 7769431.Peer-Reviewed Original ResearchConceptsIschemic regionMyocardial ischemiaBlood flowEx vivo SPECTRegional myocardial blood flowPartial coronary occlusionMicrosphere blood flowMyocardial blood flowOpen-chest canine modelVivo SPECT imagesSPECT imagesVivo planarCentral ischemic regionCoronary occlusionDemand ischemiaBMS181321Technetium-99mIntravenous injectionLiver ratioMyocardial imagingCanine modelPositive imagingHepatic clearanceLiver activityArterial sampling