2014
Excitatory Synaptic Inputs to Mouse On-Off Direction-Selective Retinal Ganglion Cells Lack Direction Tuning
Park SJ, Kim IJ, Looger LL, Demb JB, Borghuis BG. Excitatory Synaptic Inputs to Mouse On-Off Direction-Selective Retinal Ganglion Cells Lack Direction Tuning. Journal Of Neuroscience 2014, 34: 3976-3981. PMID: 24623775, PMCID: PMC3951696, DOI: 10.1523/jneurosci.5017-13.2014.Peer-Reviewed Original ResearchConceptsDirection-selective ganglion cellsOFF direction-selective ganglion cellsStarburst amacrine cellsGlutamate releaseBipolar cellsExcitatory currentsPreferred direction motionBipolar cell typesExcitatory synaptic inputsNull-direction inhibitionGABA-A receptorsWhole-cell recordingsNull-direction motionDSGC dendritesGABA releaseCholinergic inputAmacrine cellsGanglion cellsSynaptic mechanismsSynaptic inputsMammalian retinaMouse retinaIntensity-based glutamate-sensing fluorescent reporterDirection selectivityDirection tuning
2013
An optimized fluorescent probe for visualizing glutamate neurotransmission
Marvin JS, Borghuis BG, Tian L, Cichon J, Harnett MT, Akerboom J, Gordus A, Renninger SL, Chen TW, Bargmann CI, Orger MB, Schreiter ER, Demb JB, Gan WB, Hires SA, Looger LL. An optimized fluorescent probe for visualizing glutamate neurotransmission. Nature Methods 2013, 10: 162-170. PMID: 23314171, PMCID: PMC4469972, DOI: 10.1038/nmeth.2333.Peer-Reviewed Original ResearchAnimalsAstrocytesBiosensing TechniquesCaenorhabditis elegansCalcium SignalingEscherichia coli ProteinsExcitatory Postsynaptic PotentialsFluorescent DyesGlutamic AcidGreen Fluorescent ProteinsHippocampusMiceMotor CortexNeuronsPhotic StimulationPyramidal CellsRecombinant Fusion ProteinsRetinaSignal-To-Noise RatioSynaptic TransmissionZebrafish