2016
Divisive suppression explains high-precision firing and contrast adaptation in retinal ganglion cells
Cui Y, Wang YV, Park SJ, Demb JB, Butts DA. Divisive suppression explains high-precision firing and contrast adaptation in retinal ganglion cells. ELife 2016, 5: e19460. PMID: 27841746, PMCID: PMC5108594, DOI: 10.7554/elife.19460.Peer-Reviewed Original ResearchConceptsExcitatory synaptic inputsSynaptic inputsGanglion cell functionContrast adaptationRetinal ganglion cellsGanglion cell inputsComplex neural circuitsGanglion cell outputCell-intrinsic mechanismsGanglion cellsDivisive interactionMouse retinaNeural circuitsSpike responsesCell functionDivisive suppressionSensory processingCell inputSpike generation mechanismMillisecond precisionVisual processingSpike trainsCell outputSuppressionRetinaMind the Gap Junctions: The Importance of Electrical Synapses to Visual Processing
Demb JB, Singer JH. Mind the Gap Junctions: The Importance of Electrical Synapses to Visual Processing. Neuron 2016, 90: 207-209. PMID: 27100191, PMCID: PMC5751935, DOI: 10.1016/j.neuron.2016.04.007.Peer-Reviewed Original ResearchConceptsChemical synapsesRetinal circuitsIssue of NeuronElectrical synapsesSynapsesGap junctionsVisual processing
2010
NMDA Receptor Contributions to Visual Contrast Coding
Manookin MB, Weick M, Stafford BK, Demb JB. NMDA Receptor Contributions to Visual Contrast Coding. Neuron 2010, 67: 280-293. PMID: 20670835, PMCID: PMC2913150, DOI: 10.1016/j.neuron.2010.06.020.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsContrast SensitivityDizocilpine MaleateElectric ConductivityExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsGene Expression RegulationGuinea PigsIn Vitro TechniquesLightMiceMice, Inbred C57BLN-MethylaspartatePatch-Clamp TechniquesPhotic StimulationPiperidinesReceptors, N-Methyl-D-AspartateRetinaRetinal Ganglion CellsVisual PerceptionConceptsNMDA receptorsOFF alphaAlpha cellsNMDA-type glutamate receptorsOFF alpha cellsDelta cellsGanglion cell typesNMDA receptor contributionCell typesExcitatory responsesGlutamate receptorsInhibitory currentsAMPA receptorsReceptor contributionGluN2B subunitContrast sensitivityContrast codingReceptorsNMDAAMPACertain cell typesCellsVisual processingAlpha