2017
Local synaptic integration enables ON-OFF asymmetric and layer-specific visual information processing in vGluT3 amacrine cell dendrites
Chen M, Lee S, Zhou ZJ. Local synaptic integration enables ON-OFF asymmetric and layer-specific visual information processing in vGluT3 amacrine cell dendrites. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: 11518-11523. PMID: 28973895, PMCID: PMC5664540, DOI: 10.1073/pnas.1711622114.Peer-Reviewed Original ResearchConceptsInner plexiform layerAmacrine cellsSynaptic inhibitionSegregation of ONVGluT3 amacrine cellsGanglion cell typesBipolar cell terminalsSmall-field amacrine cellsOFF sublayersDendritic varicositiesPlexiform layerReceptive field sizeSynaptic processingSynaptic integrationDendritic responsesMammalian retinaOFF segregationNeuronal organizationTwo-photon imagingDendritic treeIPL depthOFF pathwaysCell terminalsDendritic functionVisual information processing
2014
An Unconventional Glutamatergic Circuit in the Retina Formed by vGluT3 Amacrine Cells
Lee S, Chen L, Chen M, Ye M, Seal RP, Zhou ZJ. An Unconventional Glutamatergic Circuit in the Retina Formed by vGluT3 Amacrine Cells. Neuron 2014, 84: 708-715. PMID: 25456497, PMCID: PMC4254642, DOI: 10.1016/j.neuron.2014.10.021.Peer-Reviewed Original ResearchConceptsDirection-selective ganglion cellsAmacrine cellsGlutamatergic circuitsGanglion cellsCalcium-dependent glutamate releaseVGluT3 amacrine cellsExcitatory glutamatergic inputGanglion cell activityOFF light responsesReceptive field structureOFF channelsGlutamate releaseGlutamatergic inputsInner retinaExcitatory inputsInhibitory neuronsBipolar cellsMouse retinaCell activityOFF responsesRetinaExcitatory interactionsVertebrate retinaCellsVisual signals