1994
Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons
Jiang C, Sigworth F, Haddad G. Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons. Journal Of Neuroscience 1994, 14: 5590-5602. PMID: 8083755, PMCID: PMC6577106, DOI: 10.1523/jneurosci.14-09-05590.1994.Peer-Reviewed Original ResearchConceptsSubstantia nigra neuronsRat substantia nigra neuronsEffects of hypoxiaGlibenclamide binding sitesEffect of ATPCell-attached patchesNeuronal survivalKATP channelsResult of Ca2Different subtypesOutward currentsNeuronal structuresFree Ca2HypoxiaMetabolic stressNeuronsDeleterious changesSingle-channel currentsChannel activityO2 deprivationInternal ATPOxygen deprivationActivationHigh Ca2Membrane potential
1991
Patch recordings from the electrocytes of Electrophorus electricus. Na currents and PNa/PK variability.
Shenkel S, Sigworth F. Patch recordings from the electrocytes of Electrophorus electricus. Na currents and PNa/PK variability. The Journal Of General Physiology 1991, 97: 1013-1041. PMID: 1650809, PMCID: PMC2216506, DOI: 10.1085/jgp.97.5.1013.Peer-Reviewed Original Research