2023
Ribbon Synapses and Retinal Disease: Review
Frederick C, Zenisek D. Ribbon Synapses and Retinal Disease: Review. International Journal Of Molecular Sciences 2023, 24: 5090. PMID: 36982165, PMCID: PMC10049380, DOI: 10.3390/ijms24065090.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPresynaptic protein complexesRibbon synapsesDefective synaptic transmissionMolecular machineryProtein complexesRetinal malfunctionSynaptic transmissionRetinal diseasesSynaptic ribbonsNeurotransmitter releaseMuscular dystrophyVisual diseaseSynapsesDiseaseSensory informationMutagenesisMachineryPresent understandingSynaptopathyVisual systemReviewPathogenesisRetinaPathology
2022
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR
Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan M, Zenisek D, Warmflash A, Owens N, Khokha M. Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. Nature Communications 2022, 13: 6681. PMID: 36335122, PMCID: PMC9637099, DOI: 10.1038/s41467-022-34363-w.Peer-Reviewed Original ResearchConceptsPluripotent cellsAdult tissue homeostasisCell fate commitmentDifferentiated cell fatesLeft-right patterningPluripotent embryonic cellsHuman embryonic stem cellsTemporal transcriptome analysisGene regulatory networksExpense of differentiationEmbryonic stem cellsGerm layer differentiationMembrane depolarizationFate commitmentPluripotent stateCell fateTranscriptome analysisRegulatory networksMyogenic lineageEmbryonic developmentTissue homeostasisDifferentiated fateEmbryonic cellsCandidate genesPluripotency
2010
Real-time visualization of complexin during single exocytic events
An SJ, Grabner CP, Zenisek D. Real-time visualization of complexin during single exocytic events. Nature Neuroscience 2010, 13: 577-583. PMID: 20383135, PMCID: PMC2860691, DOI: 10.1038/nn.2532.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Vesicular TransportAnimalsDopamineExocytosisGene Expression RegulationGreen Fluorescent ProteinsHumansMicroscopy, ConfocalNerve Tissue ProteinsNeuropeptide YPC12 CellsPhotobleachingProtein BindingPyridinium CompoundsQuaternary Ammonium CompoundsRatsRNA InterferenceSNARE ProteinsTissue Plasminogen ActivatorTransfection
2005
Recent progress towards understanding the synaptic ribbon
Prescott ED, Zenisek D. Recent progress towards understanding the synaptic ribbon. Current Opinion In Neurobiology 2005, 15: 431-436. PMID: 16023852, DOI: 10.1016/j.conb.2005.07.005.Peer-Reviewed Original Research