1997
Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract
Farman N, Talbot C, Boucher R, Fay M, Canessa C, Rossier B, Bonvalet J. Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract. American Journal Of Physiology 1997, 272: c131-c141. PMID: 9038819, DOI: 10.1152/ajpcell.1997.272.1.c131.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEpitheliumIn Situ HybridizationIsomerismRatsRats, Sprague-DawleyRespiratory SystemRNA, MessengerSodium ChannelsTissue DistributionConceptsRespiratory tractRat respiratory tractEpithelial cellsUpper airway epithelial cellsAirway epithelial cellsRespiratory epithelial cellsGamma-subunit mRNAType II pneumocytesRenal collecting tubulesBronchiolar epitheliumDistal colonCollecting tubuleRat lungSubunit expressionAlveolar cellsLarge prevalenceTracheal epitheliumGland ductsCellular expressionEpithelial surfaceMRNA levelsRespiratory physiologyGland aciniTractLuminal surface
1995
Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways
Burch L, Talbot C, Knowles M, Canessa C, Rossier B, Boucher R. Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. American Journal Of Physiology 1995, 269: c511-c518. PMID: 7653534, DOI: 10.1152/ajpcell.1995.269.2.c511.Peer-Reviewed Original ResearchConceptsAirway epitheliumSuperficial epitheliumCF airwaysGamma-ENaC mRNACF airway diseaseENaC subunit mRNAsCystic fibrosis airway epitheliaCF airway epitheliaAirway diseaseSitu hybridization studiesDuctal epitheliumCF transmembrane conductance regulator (CFTR) proteinRibonuclease protection assaysAcinar epitheliumMolecular pathogenesisCystic fibrosisChannel mRNAInhibitory regulationSubunit mRNAsEpitheliumChannel subunitsRatio of alphaAirwayRelative expressionPathogenesis