Role of the mechanosensitive ion channel Piezo1 in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Chebib F, Beyder A, Wang X, Alcaino C, Ehrlich B, Torres V. Role of the mechanosensitive ion channel Piezo1 in Autosomal Dominant Polycystic Kidney Disease (ADPKD). The FASEB Journal 2018, 32: 868.2-868.2. DOI: 10.1096/fasebj.2018.32.1_supplement.868.2.Peer-Reviewed Original ResearchAutosomal dominant polycystic kidney diseaseCalcium entryCyclic AMPMIMCD3 cellsCytoplasmic calciumFluid shear stressWild-type miceDominant polycystic kidney diseaseRenal cystogenesisFull-text articlesNon-selective cation channelsPolycystic kidney diseaseKidney diseaseExperimental Biology 2018 MeetingIntracellular calciumType miceVivo effectsPathogenic mechanismsCystic epitheliumLive-cell imagingMechanosensitive ion channelsSecretory phenotypeATP releaseMechanosensitive ion channel Piezo1Cation channels