2002
Carrier‐mediated uptake and release of taurine from Bergmann glia in rat cerebellar slices
Barakat L, Wang D, Bordey A. Carrier‐mediated uptake and release of taurine from Bergmann glia in rat cerebellar slices. The Journal Of Physiology 2002, 541: 753-767. PMID: 12068038, PMCID: PMC2290349, DOI: 10.1113/jphysiol.2001.015834.Peer-Reviewed Original ResearchConceptsRat cerebellar slicesBergmann gliaGuanidinoethyl sulphonateCerebellar slicesTaurine transporterInward currentsWhole-cell patch-clamp recordingsTaurine uptakeGABA receptor blockersTaurine transporter inhibitorRelease of taurinePatch-clamp recordingsDependent taurine transporterOrder of potencyTaurine perfusionReceptor blockersIntracellular taurineIschemic conditionsCarrier-mediated uptakeTaurine effluxOutward currentsTransporter currentsTransporter inhibitorsIntracellular perfusionGlia
1994
SR 140333, a Novel, Selective, and Potent Nonpeptide Antagonist of the NK1 Tachykinin Receptor: Characterization on the U373MG Cell Line
Oury‐Donat F, Lefevre IA, Thurneyssen O, Gauthier T, Bordey A, Feltz P, Emonds‐Alt X, Le Fur G, Soubrie P. SR 140333, a Novel, Selective, and Potent Nonpeptide Antagonist of the NK1 Tachykinin Receptor: Characterization on the U373MG Cell Line. Journal Of Neurochemistry 1994, 62: 1399-1407. PMID: 7510780, DOI: 10.1046/j.1471-4159.1994.62041399.x.Peer-Reviewed Original ResearchMeSH KeywordsAstrocytomaBinding, CompetitiveCalciumElectric ConductivityGenes, fosHumansInositol PhosphatesIodine RadioisotopesNeurokinin-1 Receptor AntagonistsPeptide FragmentsPiperidinesPotassiumPyrrolidonecarboxylic AcidQuinuclidinesReceptors, Neurokinin-1StereoisomerismSubstance PSuccinimidesTaurineTranscription, GeneticTumor Cells, CulturedConceptsSR 140333Substance PNK1 tachykinin receptor antagonistNK1 receptor activationHunter substance PNK1-selective agonistTachykinin receptor antagonistsInositol monophosphate formationNK1 tachykinin receptorsPotent nonpeptide antagonistHuman astrocytoma cell lineCell linesAstrocytoma cell linesPatch-clamp experimentsReceptor antagonistFormation of inositolTachykinin receptorsNK1 agonistU373MG cell linesCalcium mobilizationNonpeptide antagonistsRadioligand bindingReceptor activationOutward currentsMonophosphate formation