GABA Depolarizes Neuronal Progenitors of the Postnatal Subventricular Zone Via GABAA Receptor Activation
Wang DD, Krueger DD, Bordey A. GABA Depolarizes Neuronal Progenitors of the Postnatal Subventricular Zone Via GABAA Receptor Activation. The Journal Of Physiology 2003, 550: 785-800. PMID: 12807990, PMCID: PMC2343064, DOI: 10.1113/jphysiol.2003.042572.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsBarbituratesBenzodiazepinesCerebral VentriclesDose-Response Relationship, DrugElectrophysiologyGABA AntagonistsGamma-Aminobutyric AcidGlutamate DecarboxylaseIsoenzymesMembrane PotentialsMiceNeostriatumNeuronsPatch-Clamp TechniquesPicrotoxinPotassium ChannelsReceptors, GABA-AStem CellsZincConceptsRostral migratory streamGABAA receptor activationSubventricular zoneNeuronal progenitorsReceptor activationGlutamic acid decarboxylase 67Resting potentialsPostnatal mammalian brainPatch-clamp recordingsSVZ/RMSMouse brain slicesRecorded cellsCell-attached patchesGABA responsesBrain slicesNeurotransmitter GABASubset of progenitorsBenzodiazepine agonistsEmbryonic neuronsAction potentialsMammalian brainMigratory streamGABAInverse agonistSpecific receptorsBiophysical Properties and Ionic Signature of Neuronal Progenitors of the Postnatal Subventricular Zone In Situ
Wang DD, Krueger DD, Bordey A. Biophysical Properties and Ionic Signature of Neuronal Progenitors of the Postnatal Subventricular Zone In Situ. Journal Of Neurophysiology 2003, 90: 2291-2302. PMID: 12801891, DOI: 10.1152/jn.01116.2002.Peer-Reviewed Original ResearchConceptsRostral migratory streamSubventricular zonePassive membrane propertiesNeuronal progenitorsCell-attached patch-clamp recordingsNeuron-specific class IIIPostnatal mammalian brainPostnatal day 15Patch-clamp recordingsMigration of progenitorsPostnatal subventricular zoneHigh input resistanceCell-attached patchesBrain slicesOlfactory bulbMature neuronsStrong immunoreactivityTransient outwardDay 15KDR currentElectrophysiological propertiesAction potentialsMammalian brainMigratory streamClass III