2012
Preparation of acute subventricular zone slices for calcium imaging.
Lacar B, Young SZ, Platel JC, Bordey A. Preparation of acute subventricular zone slices for calcium imaging. Journal Of Visualized Experiments 2012, e4071. PMID: 23023088, PMCID: PMC3490239, DOI: 10.3791/4071.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCell typesSVZ cellsProgenitor cellsNeurogenic zonesSubventricular zoneFluo-4 AM dyeNeural progenitor cellsIntermediate progenitor cellsExtracellular signalsDiffusible signalsIntercellular signalingSVZ cell typesTime-lapse moviesCalcium indicator dyeCalcium activityIndividual cellsRostral-caudal axisNeuroblast migrationThree-dimensional arrangementAdult hippocampal subgranular zonePostnatal brainAdhesion moleculesHippocampal subgranular zoneMature astrocytesNeuroblasts
2011
Control of Adult-Born Neuron Production by Converging GABA and Glutamate Signals
Platel J, Bordey A. Control of Adult-Born Neuron Production by Converging GABA and Glutamate Signals. 2011, 395-406. DOI: 10.1007/978-4-431-53933-9_17.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSteady-state levelsStem cellsNovel epigenetic controlCell-cell signalingNeuron productionStem cell proliferationEpigenetic controlNeuroblast poolProliferative cuesNeuroblast numbersNeural stem cellsMosaic expressionNeural progenitorsHigh-affinity uptake systemUptake systemAdult-born neuronsHigh turnover rateCell proliferationNeuroblastsControl of adultsNeurotransmitter releaseNegative feedback controlNeuroblast productionImmature neuronsAdult neurogenesis
2010
NMDA Receptors Activated by Subventricular Zone Astrocytic Glutamate Are Critical for Neuroblast Survival Prior to Entering a Synaptic Network
Platel JC, Dave KA, Gordon V, Lacar B, Rubio ME, Bordey A. NMDA Receptors Activated by Subventricular Zone Astrocytic Glutamate Are Critical for Neuroblast Survival Prior to Entering a Synaptic Network. Neuron 2010, 65: 859-872. PMID: 20346761, PMCID: PMC2861893, DOI: 10.1016/j.neuron.2010.03.009.Peer-Reviewed Original ResearchConceptsAdult-born neuronsNMDA receptorsNMDAR activitySynaptic networksNeuroblast survivalGlutamate release machineryAstrocyte-like cellsLoss of neuroblastsNeonatal electroporationSpecialized astrocytesAstrocytic glutamateOlfactory bulbVesicular releaseRelease machineryReceptorsNeuroblastsNeuronsIntercellular mechanismsSurvivalGlutamateNeuroblast apoptosisAstrocytesNeurogenesisNeurotransmittersSVZ
2005
Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
Liu X, Wang Q, Haydar TF, Bordey A. Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors. Nature Neuroscience 2005, 8: 1179-1187. PMID: 16116450, PMCID: PMC1380263, DOI: 10.1038/nn1522.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBotulinum ToxinsBromodeoxyuridineCadmiumCell CountCell ProliferationChelating AgentsCyclooxygenase InhibitorsDose-Response Relationship, DrugDose-Response Relationship, RadiationDrug InteractionsEgtazic AcidElectric StimulationEnzyme InhibitorsGABA AntagonistsGamma-Aminobutyric AcidGene Expression RegulationGlial Fibrillary Acidic ProteinGreen Fluorescent ProteinsImmunohistochemistryIn Vitro TechniquesLateral VentriclesMeclofenamic AcidMembrane PotentialsMiceMice, TransgenicNeuronsNickelPatch-Clamp TechniquesPotassiumSodium Channel BlockersSpider VenomsStem CellsTetrodotoxinConceptsPostnatal subventricular zoneGFAP-expressing cellsSubventricular zoneCell cycleGABAA receptorsStem cellsNeuroblastsProgenitorsGlial fibrillary acidic proteinSVZ cellsGABAA receptor currentsGABAA receptor activationFibrillary acidic proteinReceptor activationCellsProliferationGABA releaseMouse slicesLocal cuesAcidic proteinReceptor currentsSpontaneous depolarizationsGFAPGABAReceptorsThe Postnatal Subventricular Zone: A Source of New Cells in This Old Brain
Bordey A. The Postnatal Subventricular Zone: A Source of New Cells in This Old Brain. Nepal Journal Of Neuroscience 2005, 2: 12-23. DOI: 10.3126/njn.v2i1.19977.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSubventricular zoneNon-synaptic communicationLarge germinal centersHigher cognitive centersRostral migratory streamPostnatal subventricular zoneBrain injuryPersistent neurogenesisLateral ventricleOlfactory bulbAdult brainGerminal centersOld brainMigratory streamCognitive centersNeurogenesisLateral wallStem cellsSVZBrainFuture strategiesNeuroblastsNepal JournalIntercellular signalingCells