2014
GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity
Young SZ, Lafourcade CA, Platel JC, Lin TV, Bordey A. GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity. Frontiers In Cellular Neuroscience 2014, 8: 10. PMID: 24478632, PMCID: PMC3904109, DOI: 10.3389/fncel.2014.00010.Peer-Reviewed Original ResearchSubventricular zoneStriatal neuronsSVZ cellsCalcium increaseCalcium activityNeurogenic subventricular zoneSource of GABAGABAergic striatal neuronsPatch-clamp recordingsPostnatal subventricular zoneNeural progenitor cellsGABAergic neuronsPostnatal neurogenesisGABAA receptorsGABAAR activationClamp recordingsCalcium imagingStriatal activityNeuronsProgenitor cellsGABAAxonsDepolarizationCellsDendrites
2008
GABAA receptors, anesthetics and anticonvulsants in brain development.
Henschel O, Gipson KE, Bordey A. GABAA receptors, anesthetics and anticonvulsants in brain development. CNS & Neurological Disorders - Drug Targets 2008, 7: 211-24. PMID: 18537647, PMCID: PMC2557552, DOI: 10.2174/187152708784083812.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGABAergic drugsBrain developmentLong-term cognitive deficitsMain inhibitory neurotransmitterFunction of GABANeonatal periodInhibitory neurotransmitterGABAA receptorsMature brainNeuronal excitabilitySide effectsCognitive deficitsClinical perspectiveGABACNS developmentReceptorsReceptor propertiesDrugsAnticonvulsantsAnestheticsBasic scienceReviewSedativesExcitabilityNeurotransmitters
2005
Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
Liu X, Wang Q, Haydar TF, Bordey A. Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors. Nature Neuroscience 2005, 8: 1179-1187. PMID: 16116450, PMCID: PMC1380263, DOI: 10.1038/nn1522.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBotulinum ToxinsBromodeoxyuridineCadmiumCell CountCell ProliferationChelating AgentsCyclooxygenase InhibitorsDose-Response Relationship, DrugDose-Response Relationship, RadiationDrug InteractionsEgtazic AcidElectric StimulationEnzyme InhibitorsGABA AntagonistsGamma-Aminobutyric AcidGene Expression RegulationGlial Fibrillary Acidic ProteinGreen Fluorescent ProteinsImmunohistochemistryIn Vitro TechniquesLateral VentriclesMeclofenamic AcidMembrane PotentialsMiceMice, TransgenicNeuronsNickelPatch-Clamp TechniquesPotassiumSodium Channel BlockersSpider VenomsStem CellsTetrodotoxinConceptsPostnatal subventricular zoneGFAP-expressing cellsSubventricular zoneCell cycleGABAA receptorsStem cellsNeuroblastsProgenitorsGlial fibrillary acidic proteinSVZ cellsGABAA receptor currentsGABAA receptor activationFibrillary acidic proteinReceptor activationCellsProliferationGABA releaseMouse slicesLocal cuesAcidic proteinReceptor currentsSpontaneous depolarizationsGFAPGABAReceptors