Song Chen, PhD
Associate Research Scientist in PharmacologyCards
About
Research
Publications
2024
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments
Tang W, Luan Y, Yuan Q, Li A, Chen S, Menacherry S, Young L, Wu D. LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments. Nature Communications 2024, 15: 3068. PMID: 38594269, PMCID: PMC11004178, DOI: 10.1038/s41467-024-47262-z.Peer-Reviewed Original ResearchConceptsLDL receptor-related protein 5Intracellular compartmentsPolyunsaturated fatty acidsProtein 5Ligand-binding repeatsBiologically important mechanismsAssociated with human healthImport mechanismExtracellular trap formationInhibit mTORC1Cell typesFatty acidsTrap formationN-3 polyunsaturated fatty acidsCompartmentProtect miceLDLAMyocardial injuryHomologyIschemia-reperfusionMTORC1LysosomesLRP6Human healthFATP2
2012
Structural characterization of full-length NSF and 20S particles
Chang L, Chen S, Liu C, Pan X, Jiang J, Bai X, Xie X, Wang H, Sui S. Structural characterization of full-length NSF and 20S particles. Nature Structural & Molecular Biology 2012, 19: 268-275. PMID: 22307055, DOI: 10.1038/nsmb.2237.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Vesicular TransportAdenosine DiphosphateAnimalsCricetinaeCricetulusCryoelectron MicroscopyModels, MolecularN-Ethylmaleimide-Sensitive ProteinsProtein BindingProtein Structure, QuaternaryProtein Structure, TertiarySNARE ProteinsStructural Homology, ProteinSubstrate Specificity
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