2020
Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms
Lissemore J, Booij L, Leyton M, Gravel P, Sookman D, Nordahl T, Benkelfat C. Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms. 2020, 457-478. DOI: 10.1007/978-3-030-57231-0_13.Peer-Reviewed Original ResearchSelective serotonin reuptake inhibitorsObsessive-compulsive disorderSerotonin synthesis capacityPositron emission tomographyHealthy controlsPET studiesOCD patientsSerotonin reuptake inhibitorsMost PET studiesBorderline personality disorderCognitive behavior therapySymptom onsetSerotonergic mechanismsClinical benefitSerotonergic toneSerotonergic alterationsSynthesis capacityEmission tomographySuicide attemptsSerotonin transporterPersonality disorderBehavior therapyGroup differencesDisordersPatients
2014
OCD: Serotonergic Mechanisms
Lissemore J, Leyton M, Gravel P, Sookman D, Nordahl T, Benkelfat C. OCD: Serotonergic Mechanisms. 2014, 433-450. DOI: 10.1007/978-3-642-40384-2_17.Peer-Reviewed Original ResearchSelective serotonin reuptake inhibitorsCognitive behavioral therapyObsessive-compulsive disorderPositron emission tomographySerotonergic mechanismsSerotonin reuptake inhibitorsSerotonin synthesis capacitySymptomatic improvementSymptom improvementCortico-striatoHealthy controlsSerotonin synthesisThalamic loopNeurobiological effectsEmission tomographyBrain circuitsBehavioral therapyNeurotransmitter serotoninBehavioral interventionsOCD patientsOCD pathologyRecent studiesSynthesis capacityTreatmentPatients