2020
Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms
Lissemore J, Booij L, Leyton M, Gravel P, Sookman D, Nordahl T, Benkelfat C. Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms. 2020, 457-478. DOI: 10.1007/978-3-030-57231-0_13.Peer-Reviewed Original ResearchSelective serotonin reuptake inhibitorsObsessive-compulsive disorderSerotonin synthesis capacityPositron emission tomographyHealthy controlsPET studiesOCD patientsSerotonin reuptake inhibitorsMost PET studiesBorderline personality disorderCognitive behavior therapySymptom onsetSerotonergic mechanismsClinical benefitSerotonergic toneSerotonergic alterationsSynthesis capacityEmission tomographySuicide attemptsSerotonin transporterPersonality disorderBehavior therapyGroup differencesDisordersPatients
2013
Stress‐induced dopamine release in human medial prefrontal cortex—18F‐Fallypride/PET study in healthy volunteers
Nagano‐Saito A, Dagher A, Booij L, Gravel P, Welfeld K, Casey K, Leyton M, Benkelfat C. Stress‐induced dopamine release in human medial prefrontal cortex—18F‐Fallypride/PET study in healthy volunteers. Synapse 2013, 67: 821-830. PMID: 23939822, DOI: 10.1002/syn.21700.Peer-Reviewed Original ResearchConceptsStress-induced dopamine releaseDopamine releaseHeart ratePsychological stressorsMesocortical dopamine releaseHealthy young adultsSalivary cortisol levelsStress-induced increaseMedial prefrontal cortexPositron emission tomographyMesocortical dopamine systemStress-induced decreasePresent studyTissue compartmental modelMotor zoneHealthy volunteersRostal partDopamine systemCortisol levelsWhole brainBP NDDorsal partSeparate daysEmission tomographyPET studies