2019
Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard
Pan T, Einstein S, Kappadath S, Grogg K, Gomez C, Alessio A, Hunter W, Fakhri G, Kinahan P, Mawlawi O. Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard. Medical Physics 2019, 46: 3025-3033. PMID: 31069816, PMCID: PMC7251507, DOI: 10.1002/mp.13576.Peer-Reviewed Original ResearchMeSH KeywordsHumansPhantoms, ImagingPositron Emission Tomography Computed TomographyReference StandardsConceptsAxial field-of-viewPeak noise-equivalent count rateNoise-equivalent count rateField of viewCount ratePET performanceNational Electrical Manufacturers Association NU-2Transaxial field of viewPET/CT systemTime resolutionMean energy resolutionConventional photomultiplier tubesCount rate performanceImage quality phantomSpatial resolution measurementsFiltered back projection algorithmImage qualityEnergy resolutionAcquisition timeNU 2Count lossDetector designPhotomultiplier tubeMean energyPET/MR systems
2017
Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification
Cho J, Grogg K, Min C, Zhu X, Paganetti H, Lee H, Fakhri G. Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification. Medical Physics 2017, 44: 1734-1746. PMID: 28273345, PMCID: PMC5462437, DOI: 10.1002/mp.12191.Peer-Reviewed Original ResearchMeSH KeywordsFeasibility StudiesHumansMonte Carlo MethodPhantoms, ImagingPositron-Emission TomographyProtonsConceptsProton range verificationProton rangeMonte Carlo simulationsRange verificationFall-offIn-room positron emission tomographyCarlo simulationsResidual proton rangeDose fall-offPostirradiation delayPositron emission tomography imagingSOBP beamProton beamPositron emission tomographyPositron emission tomography scanPhantom studyIn-roomFunction of depthPhantomProtonOff-setMonteAcquisition timeBeamPositron emission tomography signal
2015
National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner
Grogg K, Toole T, Ouyang J, Zhu X, Normandin M, Li Q, Johnson K, Alpert N, Fakhri G. National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner. Journal Of Nuclear Medicine 2015, 57: 646-652. PMID: 26697961, PMCID: PMC4818715, DOI: 10.2967/jnumed.115.159723.Peer-Reviewed Original ResearchConceptsNoise-equivalent count rateCount rateLoose cutsMaximum noise-equivalent counting rateSpatial resolutionDetector ringSilicon photomultipliersBrain phantomContrast recoveryAttenuation correctionPET/CT systemCrystal blockPET/CT scannerImage qualityRadial offsetNational Electrical Manufacturers AssociationActivity distributionUnique mobility capabilitiesAxial extentTransverse resolutionPhantomAxial resolutionActivity concentrationsHuman scansLayer 1 cmMapping 15O Production Rate for Proton Therapy Verification
Grogg K, Alpert N, Zhu X, Min C, Testa M, Winey B, Normandin M, Shih H, Paganetti H, Bortfeld T, Fakhri G. Mapping 15O Production Rate for Proton Therapy Verification. International Journal Of Radiation Oncology • Biology • Physics 2015, 92: 453-459. PMID: 25817530, PMCID: PMC4431894, DOI: 10.1016/j.ijrobp.2015.01.023.Peer-Reviewed Original ResearchConceptsDecay constantProton treatment planningMonte Carlo predictionsProton therapyPhantom materialTreatment deliveryPhantomThigh activityPositron emission tomographyProduction rateDynamic PET measurementsTreatment planningRabbit thigh muscleClearance rateProtonIsotopesChanges due to therapyRadionuclide speciesOxygen-15ConstantDecayImaging targetsMontePositronEffects of perfusion