2017
Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification
Cho J, Grogg K, Min C, Zhu X, Paganetti H, Lee H, Fakhri G. Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification. Medical Physics 2017, 44: 1734-1746. PMID: 28273345, PMCID: PMC5462437, DOI: 10.1002/mp.12191.Peer-Reviewed Original ResearchConceptsProton range verificationProton rangeMonte Carlo simulationsRange verificationFall-offIn-room positron emission tomographyCarlo simulationsResidual proton rangeDose fall-offPostirradiation delayPositron emission tomography imagingSOBP beamProton beamPositron emission tomographyPositron emission tomography scanPhantom studyIn-roomFunction of depthPhantomProtonOff-setMonteAcquisition timeBeamPositron emission tomography signal
2015
Mapping 15O Production Rate for Proton Therapy Verification
Grogg K, Alpert N, Zhu X, Min C, Testa M, Winey B, Normandin M, Shih H, Paganetti H, Bortfeld T, Fakhri G. Mapping 15O Production Rate for Proton Therapy Verification. International Journal Of Radiation Oncology • Biology • Physics 2015, 92: 453-459. PMID: 25817530, PMCID: PMC4431894, DOI: 10.1016/j.ijrobp.2015.01.023.Peer-Reviewed Original ResearchConceptsDecay constantProton treatment planningMonte Carlo predictionsProton therapyPhantom materialTreatment deliveryPhantomThigh activityPositron emission tomographyProduction rateDynamic PET measurementsTreatment planningRabbit thigh muscleClearance rateProtonIsotopesChanges due to therapyRadionuclide speciesOxygen-15ConstantDecayImaging targetsMontePositronEffects of perfusion
2013
Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, Fakhri G. Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3290-3297. DOI: 10.1109/tns.2013.2278140.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyIn-roomMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesRadiological decayBeamDistal endpointsProtonNative nucleiFeasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, El Fakhri G. Feasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3890-3894. PMID: 24464031, PMCID: PMC3900284, DOI: 10.1109/nssmic.2012.6551892.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesIn-roomRadiological decayBeamDistal endpointsProtonNative nuclei
2012
In Vivo Treatment Verification Using In-room PET in Proton Radiation Therapy: First Clinical Trials and Evaluation of Short-length Scan
Min C, Zhu X, Winey B, Grogg K, Fakhri G, Bortfeld T, Paganetti H, Shih H. In Vivo Treatment Verification Using In-room PET in Proton Radiation Therapy: First Clinical Trials and Evaluation of Short-length Scan. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s53-s54. DOI: 10.1016/j.ijrobp.2012.07.347.Peer-Reviewed Original Research