2017
Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification
Cho J, Grogg K, Min C, Zhu X, Paganetti H, Lee H, Fakhri G. Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification. Medical Physics 2017, 44: 1734-1746. PMID: 28273345, PMCID: PMC5462437, DOI: 10.1002/mp.12191.Peer-Reviewed Original ResearchConceptsProton range verificationProton rangeMonte Carlo simulationsRange verificationFall-offIn-room positron emission tomographyCarlo simulationsResidual proton rangeDose fall-offPostirradiation delayPositron emission tomography imagingSOBP beamProton beamPositron emission tomographyPositron emission tomography scanPhantom studyIn-roomFunction of depthPhantomProtonOff-setMonteAcquisition timeBeamPositron emission tomography signal
2014
A Recommendation on How to Analyze In-Room PET for In Vivo Proton Range Verification Using a Distal PET Surface Method
Min C, Zhu X, Grogg K, Fakhri G, Winey B, Paganetti H. A Recommendation on How to Analyze In-Room PET for In Vivo Proton Range Verification Using a Distal PET Surface Method. Technology In Cancer Research & Treatment 2014, 14: 320-325. PMID: 25246517, PMCID: PMC4898041, DOI: 10.1177/1533034614547457.Peer-Reviewed Original ResearchConceptsIn vivo range verificationIn-room positron emission tomographyRange verificationBeam passageIn vivo proton range verificationIn-roomIn-room PET scannerPositron emission tomography activityProton beam rangeProton range verificationSingle-field treatmentsProton beam deliveryAverage range differencesBeam rangeBeam deliveryPET scannerRoot-mean-square deviationPositron emission tomographyBeamRange differencesLevel surfaceActive lineActivity levelsLocal variationsTreatment course
2013
Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, Fakhri G. Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3290-3297. DOI: 10.1109/tns.2013.2278140.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyIn-roomMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesRadiological decayBeamDistal endpointsProtonNative nucleiFeasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, El Fakhri G. Feasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3890-3894. PMID: 24464031, PMCID: PMC3900284, DOI: 10.1109/nssmic.2012.6551892.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesIn-roomRadiological decayBeamDistal endpointsProtonNative nuclei
2012
MO‐A‐213AB‐07: Evaluation of Distal Dose Surface with In‐Room PET for Proton Therapy Monitoring
Min C, Zhu X, Grogg K, Winey B, Fakhri G, Bortfeld T, Shih H, Paganetti H. MO‐A‐213AB‐07: Evaluation of Distal Dose Surface with In‐Room PET for Proton Therapy Monitoring. Medical Physics 2012, 39: 3860-3860. PMID: 28517508, DOI: 10.1118/1.4735759.Peer-Reviewed Original ResearchProton dose distributionsMeasured PET imagesDose surfaceDose distributionIn-roomMonte CarloProton therapy monitoringBeam's eye viewPET activitySimulated PET imagesPET imagingGantry roomsTreatment verificationTreatment headBeam deliveryClinical trialsProton therapyPassive scatteringMC simulationsBeam directionTreated volumeRoot-mean-square deviationBeamImage registrationSimulated PET