2019
Corticolimbic fast-tracking: enhanced multimodal integration in functional neurological disorder
Diez I, Ortiz-Terán L, Williams B, Jalilianhasanpour R, Ospina J, Dickerson B, Keshavan M, LaFrance W, Sepulcre J, Perez D. Corticolimbic fast-tracking: enhanced multimodal integration in functional neurological disorder. Journal Of Neurology Neurosurgery & Psychiatry 2019, 90: 929. PMID: 30850473, PMCID: PMC6625895, DOI: 10.1136/jnnp-2018-319657.Peer-Reviewed Original ResearchConceptsFunctional neurological disorderLeft anterior insulaRight anterior insulaAnterior insulaSymptom severityWithin-group analysisPathophysiology of functional neurological disorderFunctional neurological disorder cohortsMotor functional neurological disorderRight laterobasal amygdalaMultimodal integration networkBilateral posterior insulaMiddle cingulate cortexMultimodal integration areasLaterobasal amygdalaDisorder subscaleCentromedial amygdalaCingulate cortexInteroceptive processingAffective disturbancesPatient-reported symptom severityPosterior insulaWithin-group associationsAmygdalar nucleiBetween-group differences
2016
Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms
Beucke J, Sepulcre J, Buhlmann U, Kathmann N, Moody T, Feusner J. Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms. European Neuropsychopharmacology 2016, 26: 1657-1666. PMID: 27514293, PMCID: PMC5316290, DOI: 10.1016/j.euroneuro.2016.04.011.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderBody dysmorphic disorderFunctional magnetic resonance imagingOrbitofrontal cortexDysmorphic disorderSymptom severityFunctional connectivityYale-Brown Obsessive-Compulsive ScaleResting-state functional connectivityDegree connectivityFace processing taskObsessive-Compulsive ScaleBrain-behavior associationsDegree of functional connectivityCompulsive symptomsObsessive-compulsiveAmygdalar connectivityCompulsive behaviorsObsessive thoughtsBrain hyperactivitySymptom provocationDistant connectionsBrain areasDiagnostic groupsBasal ganglia