2020
Central neurogenetic signatures of the visuomotor integration system
Bueichekú E, Aznárez-Sanado M, Diez I, Uquillas F, Ortiz-Terán L, Qureshi A, Suñol M, Basaia S, Ortiz-Terán E, Pastor M, Sepulcre J. Central neurogenetic signatures of the visuomotor integration system. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 6836-6843. PMID: 32144139, PMCID: PMC7104395, DOI: 10.1073/pnas.1912429117.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAutism Spectrum DisorderBrain MappingCalcium ChannelsCohort StudiesEpilepsies, MyoclonicFemaleHumansMaleMiddle AgedMotor CortexNAV1.1 Voltage-Gated Sodium ChannelNeurodevelopmental DisordersPrader-Willi SyndromeProteinsPsychomotor PerformanceT-Box Domain ProteinsVisual CortexVisual PerceptionConceptsAutism spectrum disorderVisuomotor integrationNeurogenetic syndromesAllen Human Brain AtlasHuman cortexHuman Brain AtlasWilliams syndromeSpectrum disorderConnectome approachVisuomotor impairmentFragile XSystems neuroscienceVisuomotorHuman brainCortexFunctional impairmentBiological basisPrader-WilliBrain atlasesExpression traitsNeuronal organizationGene expression traitsDisordersImpairmentNeural development
2019
Sensory-to-Cognitive Systems Integration Is Associated With Clinical Severity in Autism Spectrum Disorder
Martínez K, Martínez-García M, Marcos-Vidal L, Janssen J, Castellanos F, Pretus C, Villarroya Ó, Pina-Camacho L, Díaz-Caneja C, Parellada M, Arango C, Desco M, Sepulcre J, Carmona S. Sensory-to-Cognitive Systems Integration Is Associated With Clinical Severity in Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 422-433. PMID: 31260788, DOI: 10.1016/j.jaac.2019.05.033.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutism Spectrum DisorderBrainBrain MappingChildCognitionHumansMagnetic Resonance ImagingMaleNeural PathwaysSystems IntegrationConceptsAutism spectrum disorderSpectrum disorderAutism spectrum disorder groupHigh-functioning ASD individualsResting state functional magnetic resonance imagingFunctional magnetic resonance imagingHealthy controlsVineland Adaptive Behavior ScalesUnimodal regionsImpaired multisensory integrationAssociated with increased clinical severityMultisensory integration deficitsAdaptive Behavior ScalesFunctional connectivity analysisSocial Communication QuestionnaireSocial Responsiveness ScalePatterns of hyper-Connection integrityMultimodal sensory integrationFunctional dysconnectivityBrain systemsASD groupMode networkFronto-parietalHigh-functioning