Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis
Pampliega O, Domercq M, Villoslada P, Sepulcre J, Rodríguez-Antigüedad A, Matute C. Association of an EAAT2 polymorphism with higher glutamate concentration in relapsing multiple sclerosis. Journal Of Neuroimmunology 2008, 195: 194-198. PMID: 18378006, DOI: 10.1016/j.jneuroim.2008.01.011.Peer-Reviewed Original ResearchConceptsMultiple sclerosisGlutamate homeostasisMS patientsPlasma glutamate levelsRelapsing multiple sclerosisGlutamate transporter EAAT2Glutamate plasma levelsGlutamate levelsRelapsing MSPlasma levelsControl subjectsTransporter expressionTransporter EAAT2Glutamate excitotoxicityGlutamate concentrationTissue damageMutant genotypesGlutamateEAAT2PatientsSclerosisPolymorphismHomeostasis