2023
Magnetic Resonance-Guided Focused Ultrasound Thalamotomy Rebalances Atypical Functional Hierarchy in Patients with Essential Tremor
Lin J, Kang X, Lu H, Zhang D, Bian X, Zhou J, Hu J, Zhang D, Sepulcre J, Pan L, Lou X. Magnetic Resonance-Guided Focused Ultrasound Thalamotomy Rebalances Atypical Functional Hierarchy in Patients with Essential Tremor. Neurotherapeutics 2023, 20: 1755-1766. PMID: 37843768, PMCID: PMC10684443, DOI: 10.1007/s13311-023-01442-9.Peer-Reviewed Original ResearchMeSH KeywordsEssential TremorHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyRetrospective StudiesThalamusTreatment OutcomeTremorConceptsMRgFUS thalamotomyET patientsEssential tremorMagnetic resonance-guided focused ultrasoundMatched health controlsPostoperative 6 monthsTremor symptomsHealth controlsFunctional MR imagingMRgFUSPatientsFeatures of Parkinson's diseaseThalamotomyRobust alterationsMR imagingPosterior cingulate cortexFocused ultrasoundCingulate cortexSymptomsNeurological diseasesAlterationsParkinson's diseaseSymptom predictionDiseaseTremor
2017
Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease
Xia C, Makaretz S, Caso C, McGinnis S, Gomperts S, Sepulcre J, Gomez-Isla T, Hyman B, Schultz A, Vasdev N, Johnson K, Dickerson B. Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease. JAMA Neurology 2017, 74: 427-436. PMID: 28241163, PMCID: PMC5470368, DOI: 10.1001/jamaneurol.2016.5755.Peer-Reviewed Original ResearchConceptsStructural magnetic resonance imagingAlzheimer's diseaseCortical atrophyHyperphosphorylated tau proteinClinical phenotypeTau in vivoAssociation in vivoAtypical Alzheimer's diseaseMagnetic resonance imagingTau proteinMeasure amyloid burdenPositron emission tomographicNeurofibrillary tanglesMeasure cortical thicknessOutpatient referral centerDisease-modifying therapeuticsTau PET imagingCarbon 11-labeled Pittsburgh Compound BCognitive functionIn vivo evidenceCortical regionsResonance imagingPostmortem studiesCortical thicknessNeurodegenerative diseases