Amyloid‐β and tau pathologies relate to distinctive brain dysconnectomics in autosomal‐dominant Alzheimer’s disease
Guzman‐Velez E, Diez I, Schoemaker D, Pardilla‐Delgado E, Fox‐Fuller J, Vila‐Castelar C, Baena A, Sperling R, Johnson K, Lopera F, Sepulcre J, Quiroz Y. Amyloid‐β and tau pathologies relate to distinctive brain dysconnectomics in autosomal‐dominant Alzheimer’s disease. Alzheimer's & Dementia 2021, 17 DOI: 10.1002/alz.056134.Peer-Reviewed Original ResearchAmyloid-bWeighted-degreesTau pathologyAutosomal-dominant Alzheimer's diseaseNon-carriersAutosomal-dominant ADTau burdenPredicting disease riskTau seedsPresenilin-1Tau propagationPSEN-1AD progressionSignificance thresholdAlzheimer's diseaseTauGraph-based network analysisMutation carriersTau-PETPosterior cingulate cortexMutationsConnectivity mapsGenetically-determinedResting-state fMRINetwork analysis