2021
Cortical Networks of Creative Ability Trace Gene Expression Profiles of Synaptic Plasticity in the Human Brain
Orwig W, Diez I, Bueichekú E, Vannini P, Beaty R, Sepulcre J. Cortical Networks of Creative Ability Trace Gene Expression Profiles of Synaptic Plasticity in the Human Brain. Frontiers In Human Neuroscience 2021, 15: 694274. PMID: 34381343, PMCID: PMC8350487, DOI: 10.3389/fnhum.2021.694274.Peer-Reviewed Original ResearchSynaptic plasticityOrganization of brain networksFunctional neuroimaging dataHuman brainCreative abilitiesBrain networksFunctional connectivityNeuroimaging phenotypesGraph theory approachNeuroimaging dataNeural plasticityCortical networksBiological basisCortical distributionConnectivity mapsDistributed connectivityCreative thinkingDistribution of genesGene expression distributionSets of genesGene expression informationBrainSynaptic assemblyGene expression profilesNeuroimagingUnveiling the neuroimaging-genetic intersections in the human brain
Diez I, Sepulcre J. Unveiling the neuroimaging-genetic intersections in the human brain. Current Opinion In Neurology 2021, 34: 480-487. PMID: 34227572, PMCID: PMC8265485, DOI: 10.1097/wco.0000000000000952.Peer-Reviewed Original ResearchConceptsSingle-cell transcriptomic dataExpression of genesFunctional annotationGenetic networksGenetic dataTranscriptome dataTranscriptomic datasetsBrain genesGenesBrain phenotypesBrain expressionBiological mechanismsNeuroimaging workNeuroimaging mapsBrain-wideNeuroimaging findingsLife spanExpressionTranscriptomeHuman brainNeuroimaging
2016
Advanced Neuroimaging Methods Towards Characterization of Early Stages of Alzheimer’s Disease
Sepulcre J, Masdeu J. Advanced Neuroimaging Methods Towards Characterization of Early Stages of Alzheimer’s Disease. Methods In Molecular Biology 2016, 1303: 509-519. PMID: 26235088, DOI: 10.1007/978-1-4939-2627-5_31.Peer-Reviewed Original ResearchConceptsBlood oxygen level-dependentFunctional magnetic resonance imagingAlzheimer's diseaseEarly stages of Alzheimer's diseaseOxygen level-dependentMagnetic resonance imagingStages of Alzheimer's diseaseNeurobiological changesStructural neuroimagingBrain networksBrain regionsBrains of patientsPostmortem studiesLevel-dependentNeurobiology of ADFunctional networksPostmortem dataBrainQuiet wakefulnessTau depositionResonance imagingTherapeutic interventionsNetwork propertiesNeurobiologyNeuroimaging