Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis
Toledo J, Sepulcre J, Salinas-Alaman A, García-Layana A, Murie-Fernandez M, Bejarano B, Villoslada P. Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis. Multiple Sclerosis Journal 2008, 14: 906-912. PMID: 18573835, DOI: 10.1177/1352458508090221.Peer-Reviewed Original ResearchConceptsRetinal nerve fiber layerHeidelberg retinal tomographyOptical coherence tomographyMultiple sclerosisRetinal nerve fiber layer thickness measurementsRetinal nerve fiber layer atrophyRetinal nerve fiber layer thicknessCompare optical coherence tomographyNerve fiber layer atrophyNerve fiber layerAssociated with physical disabilityRetinal tomographyFiber layerCoherence tomographyAxonal lossNeurological examinationMatched controlsSymbol Digit Modalities TestTissue changesPatientsCognitive disabilitiesAtrophyMS evolutionDetect thinningTomography