2023
Magnetic Resonance-Guided Focused Ultrasound Thalamotomy Rebalances Atypical Functional Hierarchy in Patients with Essential Tremor
Lin J, Kang X, Lu H, Zhang D, Bian X, Zhou J, Hu J, Zhang D, Sepulcre J, Pan L, Lou X. Magnetic Resonance-Guided Focused Ultrasound Thalamotomy Rebalances Atypical Functional Hierarchy in Patients with Essential Tremor. Neurotherapeutics 2023, 20: 1755-1766. PMID: 37843768, PMCID: PMC10684443, DOI: 10.1007/s13311-023-01442-9.Peer-Reviewed Original ResearchConceptsMRgFUS thalamotomyET patientsEssential tremorMagnetic resonance-guided focused ultrasoundMatched health controlsPostoperative 6 monthsTremor symptomsHealth controlsFunctional MR imagingMRgFUSPatientsFeatures of Parkinson's diseaseThalamotomyRobust alterationsMR imagingPosterior cingulate cortexFocused ultrasoundCingulate cortexSymptomsNeurological diseasesAlterationsParkinson's diseaseSymptom predictionDiseaseTremor
2011
Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging.
Stufflebeam S, Liu H, Sepulcre J, Tanaka N, Buckner R, Madsen J. Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. Journal Of Neurosurgery 2011, 114: 1693-7. PMID: 21351832, PMCID: PMC3248962, DOI: 10.3171/2011.1.jns10482.Peer-Reviewed Original ResearchConceptsEpileptic dischargesRefractory epilepsyMedically refractory epilepsyFocal epileptic dischargesLocalized epileptic dischargesSeizure onset zoneMagnetic resonance imagingFunctional connectivity magnetic resonance imagingStatistically significant increaseSurgical treatmentEpileptogenic areaSpontaneous brain activityInvasive electroencephalographyOnset zonePatientsResonance imagingMR imagingHigh-spatial resolutionNoninvasive methodSignificant increasePresurgical mappingFocal regionFCMREpilepsy
2007
Fractal dimension and white matter changes in multiple sclerosis
Esteban F, Sepulcre J, de Mendizábal N, Goñi J, Navas J, de Miras J, Bejarano B, Masdeu J, Villoslada P. Fractal dimension and white matter changes in multiple sclerosis. NeuroImage 2007, 36: 543-549. PMID: 17499522, DOI: 10.1016/j.neuroimage.2007.03.057.Peer-Reviewed Original ResearchConceptsMultiple sclerosisHealthy controlsCentrum semiovale levelWhite matterConventional MR imagingGray-white matter interfaceMR imaging sectionsVoxel-based morphometry approachCentral nervous systemConventional magnetic resonanceWhite matter changesWM abnormalitiesPatientsMR imagingMS lesionsNervous systemBrain white matterMatter changesMagnetic resonanceNAWMBrain WMBrains of patientsLesionsBrainEarly phase