2022
Intentionality of Self-Generated Thought: Contributions of Mind Wandering to Creativity
Orwig W, Diez I, Bueichekú E, Kelly C, Sepulcre J, Schacter D. Intentionality of Self-Generated Thought: Contributions of Mind Wandering to Creativity. Creativity Research Journal 2022, 35: 471-480. PMID: 37576950, PMCID: PMC10414778, DOI: 10.1080/10400419.2022.2120286.Peer-Reviewed Original ResearchUnintentional mind wanderingResting-state network connectivityMind wanderingWandering tendenciesInvolvement of prefrontal areasAssociated with mind wanderingResting-state fMRI scansTrait-level measuresContribution of mindfulnessLeft temporal poleDivergent thinking taskSelf-report measuresIntentional mind wanderingGraph theory analysisFMRI scanningNeural correlatesPrefrontal areasTemporal poleThinking tasksConnectivity differencesCognitive processesBehavioral levelNeuroimaging analysisNetwork connectivityDegree connectivity
2016
Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms
Beucke J, Sepulcre J, Buhlmann U, Kathmann N, Moody T, Feusner J. Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms. European Neuropsychopharmacology 2016, 26: 1657-1666. PMID: 27514293, PMCID: PMC5316290, DOI: 10.1016/j.euroneuro.2016.04.011.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderBody dysmorphic disorderFunctional magnetic resonance imagingOrbitofrontal cortexDysmorphic disorderSymptom severityFunctional connectivityYale-Brown Obsessive-Compulsive ScaleResting-state functional connectivityDegree connectivityFace processing taskObsessive-Compulsive ScaleBrain-behavior associationsDegree of functional connectivityCompulsive symptomsObsessive-compulsiveAmygdalar connectivityCompulsive behaviorsObsessive thoughtsBrain hyperactivitySymptom provocationDistant connectionsBrain areasDiagnostic groupsBasal ganglia
2013
Abnormally High Degree Connectivity of the Orbitofrontal Cortex in Obsessive-Compulsive Disorder
Beucke J, Sepulcre J, Talukdar T, Linnman C, Zschenderlein K, Endrass T, Kaufmann C, Kathmann N. Abnormally High Degree Connectivity of the Orbitofrontal Cortex in Obsessive-Compulsive Disorder. JAMA Psychiatry 2013, 70: 619-629. PMID: 23740050, DOI: 10.1001/jamapsychiatry.2013.173.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderNeurobiological models of obsessive-compulsive disorderModels of obsessive-compulsive disorderOrbitofrontal cortexUnmedicated patientsAntidepressant medicationBasal gangliaSymptom severityObsessive-compulsive disorder symptom severityConsistent with neurobiological modelsTreated with antidepressant medicationResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingOCD symptom severityReduced local connectivityLocal functional connectivityBrain network propertiesDegree connectivityStatistical parametric mappingVentral striatumCase-control cross-sectional studyCorticostriatal circuitryNeurobiological modelsBrain circuitsConnectivity alterations