2010
Functional-Anatomic Fractionation of the Brain's Default Network
Andrews-Hanna J, Reidler J, Sepulcre J, Poulin R, Buckner R. Functional-Anatomic Fractionation of the Brain's Default Network. Neuron 2010, 65: 550-562. PMID: 20188659, PMCID: PMC2848443, DOI: 10.1016/j.neuron.2010.02.005.Peer-Reviewed Original ResearchConceptsMedial temporal lobe subsystemNetwork of brain regionsBrain's default networkHuman functional imagingPersonally significant eventsDefault networkMidline coreSelf-relevanceMental sceneSpontaneous cognitionBrain regionsFunctional imagingSpontaneous actsSignificant eventsCognitionIntrinsic activityMemoryDecision makingBrainHypothesis
2009
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease
Buckner R, Sepulcre J, Talukdar T, Krienen F, Liu H, Hedden T, Andrews-Hanna J, Sperling R, Johnson K. Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease. Journal Of Neuroscience 2009, 29: 1860-1873. PMID: 19211893, PMCID: PMC2750039, DOI: 10.1523/jneurosci.5062-08.2009.Peer-Reviewed Original ResearchConceptsIntrinsic functional connectivityCortical hubsFunctional connectivityPositron emission tomography amyloid imagingAlzheimer's diseaseActive task statesFunctional magnetic resonance imaging datasetsDefault networkPrefrontal cortexHeteromodal areasPosterior cingulateBrain areasAccurate reference mapAssociation cortexCortical network architectureTask statesOlder controlsInformation processingCortexAmyloid-beta depositionHuman cerebral cortexCerebral cortexPatterns of vulnerabilityConsensus estimateBrain diseases