Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder
Perez D, Williams B, Matin N, LaFrance W, Costumero-Ramos V, Fricchione G, Sepulcre J, Keshavan M, Dickerson B. Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder. Journal Of Neurology Neurosurgery & Psychiatry 2017, 88: 1052. PMID: 28844071, DOI: 10.1136/jnnp-2017-316359.Peer-Reviewed Original ResearchConceptsPathophysiology of functional neurological disorderFunctional neurological disorderInsular volumeTrait anxietyWithin-group analysisSalience networkAmygdalar volumeMental healthVolumetric differencesFunctional neurological disorder cohortsEmotional problemsSevere physical health impairmentMotor FND subtypesSecondary within-group analysisRight amygdalar volumeElevated trait anxietySalience network regionsPhysical health impairmentAssociated with mental healthNeurological symptom severityHealth statusAssociated with role limitationsImpaired mental healthAffective symptomsWell-being deficits