Publications

2025

16 Metabolic Syndrome and ObesityAlonso W, Canapari C. 16 Metabolic Syndrome and Obesity. 2025, 175-184. DOI: 10.1016/b978-0-323-75566-5.00016-2.
Association of delayed asthma diagnosis with asthma exacerbations in childrenWi C, Ryu E, King K, Kwon J, Bublitz J, Park M, Chiarella S, Greenwood J, Pongdee T, Myers L, Nordlund B, Sohn S, Sagheb E, Kshatriya B, Watson D, Liu H, Sheares B, Davis C, Schulz W, Juhn Y. Association of delayed asthma diagnosis with asthma exacerbations in children. Journal Of Allergy And Clinical Immunology Global 2025, 100409. DOI: 10.1016/j.jacig.2025.100409.

2024

Ezrin drives adaptation of monocytes to the inflamed lung microenvironmentGudneppanavar R, Di Pietro C, H Öz H, Zhang P, Cheng E, Huang P, Tebaldi T, Biancon G, Halene S, Hoppe A, Kim C, Gonzalez A, Krause D, Egan M, Gupta N, Murray T, Bruscia E. Ezrin drives adaptation of monocytes to the inflamed lung microenvironment. Cell Death & Disease 2024, 15: 864. PMID: 39613751, PMCID: PMC11607083, DOI: 10.1038/s41419-024-07255-8.
Pediatric Pulmonary Fellowship Interviews: The More Options, the BetterRichard K, Kirkby S, Bishay L, Martinez-Fernandez T, Iwanaga K, Sheares B, De A, Nelson B. Pediatric Pulmonary Fellowship Interviews: The More Options, the Better. ATS Scholar 2024 DOI: 10.34197/ats-scholar.2024-0052br.
The Next Frontier: Defining and Optimizing Treatments for Patients with T2 Low AsthmaZidan E, Wilson G, Shin J, Chupp G. The Next Frontier: Defining and Optimizing Treatments for Patients with T2 Low Asthma. Annals Of Allergy Asthma & Immunology 2024 PMID: 39414022, DOI: 10.1016/j.anai.2024.10.013.
CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and cystic fibrosis miceÖz H, Braga C, Gudneppanavar R, Di Pietro C, Huang P, Zhang P, Krause D, Egan M, Murray T, Bruscia E. CCR2+ monocytes are dispensable to resolve acute pulmonary Pseudomonas aeruginosa infections in WT and cystic fibrosis mice. Journal Of Leukocyte Biology 2024, qiae218. PMID: 39365279, DOI: 10.1093/jleuko/qiae218.
Keeping Race and Diversity Relevant in Medical Education.Baugh A, Akgün K, Rusk A, Adelson V, Afolabi F, Crowder S, Ferreira J, Gurubhagavatula I, Lovinsky-Desir S, Lawrence K, Myers L, Niranjan S, Schotland H, Sheares B, Sullivan D, Wisnivesky J, Sweet S. Keeping Race and Diversity Relevant in Medical Education. Annals Of The American Thoracic Society 2024, 21: 1365-1371. PMID: 39078251, PMCID: PMC11451892, DOI: 10.1513/annalsats.202403-322ps.
Research Priorities in Pediatric Asthma Morbidity: Addressing the Impacts of Systemic Racism on Children with Asthma in the United States. An Official American Thoracic Society Workshop ReportLovinsky-Desir S, Riley I, Bryant-Stephens T, De Keyser H, Forno E, Kozik A, Louisias M, Matsui E, Sheares B, Thakur N, Apter A, Beck A, Bentley-Edwards K, Berkowitz C, Braxton C, Dean J, Jones C, Koinis-Mitchell D, Okelo S, Taylor-Cousar J, Teach S, Wechsler M, Gaffin J, Federico M. Research Priorities in Pediatric Asthma Morbidity: Addressing the Impacts of Systemic Racism on Children with Asthma in the United States. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2024, 21: 1349-1364. PMID: 39352175, PMCID: PMC11451894, DOI: 10.1513/annalsats.202407-767st.
Caregivers of children with asthma alarmed by climate change: a cross‐sectional studyGodse S, Shabanova V, Ragavan M, Mitchell M, Chen L, Flom J, Sheares B. Caregivers of children with asthma alarmed by climate change: a cross‐sectional study. Pediatric Pulmonology 2024, 59: 3677-3685. PMID: 39323113, DOI: 10.1002/ppul.27288.
285 Development of an electrochemiluminescence CFTR immunoassayBrowne J, Lee J, Peterec K, Garrison A, Bruscia E, Saltzman W, Egan M. 285 Development of an electrochemiluminescence CFTR immunoassay. Journal Of Cystic Fibrosis 2024, 23: s152. DOI: 10.1016/s1569-1993(24)01125-1.
395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis miceBraga C, Mancuso R, Thompson E, Oez H, Gudneppannavar R, Zhang P, Huang P, Egan M, Murray T, Krause D, Bruscia E. 395 Altered hematopoiesis and functional decline of hematopoietic stem cells in cystic fibrosis mice. Journal Of Cystic Fibrosis 2024, 23: s207-s208. DOI: 10.1016/s1569-1993(24)01235-9.
264 Poly(amine-co-ester) nanoparticle delivery of CFTR mRNA shows restoration of CFTR activity in cystic fibrosis airway modelsGarrison A, Lee J, Browne J, Akhtar L, Peterec K, Suberi A, Eaton D, Ene M, Zhang X, Whang C, Oez H, Kizilirmak T, Bruscia E, Piotrowski-Daspit A, Saltzman W, Egan M. 264 Poly(amine-co-ester) nanoparticle delivery of CFTR mRNA shows restoration of CFTR activity in cystic fibrosis airway models. Journal Of Cystic Fibrosis 2024, 23: s140-s141. DOI: 10.1016/s1569-1993(24)01104-4.
256 Primary mouse tracheal basal cells transplanted into CFTR−/− mice reconstitute CFTR functionChen K, Berical A, Oez H, Braga C, Garrison A, Gudneppanavar R, Egan M, Kotton D, Bruscia E, Hawkins F. 256 Primary mouse tracheal basal cells transplanted into CFTR−/− mice reconstitute CFTR function. Journal Of Cystic Fibrosis 2024, 23: s136. DOI: 10.1016/s1569-1993(24)01096-8.
219 CFTR dysfunction shapes airway immune cell compositions contributing to lung pathogenesis in children with cystic fibrosisKizilirmak T, Yin H, Garrison A, Browne J, Bruscia E, Egan M, Britto C. 219 CFTR dysfunction shapes airway immune cell compositions contributing to lung pathogenesis in children with cystic fibrosis. Journal Of Cystic Fibrosis 2024, 23: s119. DOI: 10.1016/s1569-1993(24)01059-2.
Patient-Reported Outcome Measure Development and Validation: A Primer for CliniciansKosinski M, Nelson L, Stanford R, Flom J, Schatz M. Patient-Reported Outcome Measure Development and Validation: A Primer for Clinicians. The Journal Of Allergy And Clinical Immunology In Practice 2024, 12: 2554-2561. PMID: 39181327, DOI: 10.1016/j.jaip.2024.08.030.
Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutationGupta A, Barone C, Quijano E, Piotrowski-Daspit A, Perera J, Riccardi A, Jamali H, Turchick A, Zao W, Saltzman W, Glazer P, Egan M. Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation. Journal Of Cystic Fibrosis 2024 PMID: 39107154, DOI: 10.1016/j.jcf.2024.07.009.
FPIES: Definitions, epidemiology, clinical manifestationsWong KH, Leeds S, Nowak-Wegrzyn A. FPIES: definitions, epidemiology, clinical manifestations. Encyclopedia of Food Allergy, edited by Scott Sicherer, Elsevier, 2024
Scholarly Activity during Neonatal–Perinatal Medicine FellowshipDyess N, Myers P, Dammann C, Chess P, Abramson E, Andy C, Weiss P. Scholarly Activity during Neonatal–Perinatal Medicine Fellowship. American Journal Of Perinatology 2024, 42: 075-083. PMID: 38749483, DOI: 10.1055/a-2327-3908.
Quality Improvement Initiative Enhances Outpatient Pediatric Pulmonology Follow-up for Premature Infants with Bronchopulmonary DysplasiaBrumer E, Godse S, Chandrasekar L, Kizilirmak T, Blythe E, Gozzo Y, Peterec S, Kandil S, Grossman M, Chen L, Weiss P, Sheares B. Quality Improvement Initiative Enhances Outpatient Pediatric Pulmonology Follow-up for Premature Infants with Bronchopulmonary Dysplasia. Pediatric Quality And Safety 2024, 9: e736. PMID: 38854502, PMCID: PMC11161285, DOI: 10.1097/pq9.0000000000000736.
Concordance of provider chart notation and guideline-based classification of asthma severityKroll H, Feinberg T, Soffer G, Reznik M. Concordance of provider chart notation and guideline-based classification of asthma severity. Journal Of Asthma 2024, 61: 1402-1411. PMID: 38717912, DOI: 10.1080/02770903.2024.2353106.
Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoysPiotrowski-Daspit A, Bracaglia L, Eaton D, Richfield O, Binns T, Albert C, Gould J, Mortlock R, Egan M, Pober J, Saltzman W. Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys. Nature Communications 2024, 15: 4247. PMID: 38762483, PMCID: PMC11102454, DOI: 10.1038/s41467-024-48442-7.
Chronic lung inflammation disrupts the quiescent state of hematopoietic stem cells in a cystic fibrosis mouse modelBraga C, Mancuso R, Thompson E, Oez H, Gudneppanavar R, Zhang P, Huang P, Murray T, Egan M, Krause D, Bruscia E. Chronic lung inflammation disrupts the quiescent state of hematopoietic stem cells in a cystic fibrosis mouse model. The Journal Of Immunology 2024, 212: 0062_6002-0062_6002. DOI: 10.4049/jimmunol.212.supp.0062.6002.
Ezrin drives adaptation of monocytes to the inflamed lung microenvironment.Gudneppanavar R, Di Pietro C, Oez H, Zhang P, Huang P, Braga C, Tebaldi T, Biancon G, Kim C, Gonzalez A, Halene S, Krause D, Egan M, Gupta N, Murray T, Bruscia E. Ezrin drives adaptation of monocytes to the inflamed lung microenvironment. The Journal Of Immunology 2024, 212: 0078_5418-0078_5418. DOI: 10.4049/jimmunol.212.supp.0078.5418.
Understanding Impact of CFTR Dysfunction on Airway Immune Cell Composition in Early Lung Disease PathogenesisKockar Kizilirmak T, Yin H, Garrison A, Bruscia E, Egan M, Britto-Leon C. Understanding Impact of CFTR Dysfunction on Airway Immune Cell Composition in Early Lung Disease Pathogenesis. 2024, a6357-a6357. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6357.
Parental Perspectives: Pediatric Asthma and the Health Impacts of Climate ChangeGodse S, Flom J, Kaur A, Shabanova V, Chen L, Sheares B. Parental Perspectives: Pediatric Asthma and the Health Impacts of Climate Change. 2024, a6219-a6219. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6219.
Advocacy and Health Equity The Role of the Pediatric PulmonologistSadreameli S, Coates A, Sheares B. Advocacy and Health Equity The Role of the Pediatric Pulmonologist. Clinics In Chest Medicine 2024, 45: 771-783. PMID: 39069337, DOI: 10.1016/j.ccm.2024.02.024.
Screening and Evaluation of Sleep Disturbances and Sleep Disorders in Children and AdolescentsBaddam S, Canapari C, Van de Grift J, McGirr C, Nasser A, Crowley M. Screening and Evaluation of Sleep Disturbances and Sleep Disorders in Children and Adolescents. Psychiatric Clinics Of North America 2024, 47: 65-86. PMID: 38302214, DOI: 10.1016/j.psc.2023.06.005.
When lungs and weights tell different storiesGodse S, Brumer E, Kizilirmak T, Canapari C, Silva C, Morotti R, Jiang Y, Jeffries L, Chen L, Panacherry S. When lungs and weights tell different stories. Pediatric Pulmonology 2024, 59: 1047-1059. PMID: 38353400, DOI: 10.1002/ppul.26832.
Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian HamstersDi Pietro C, Haberman A, Lindenbach B, Smith P, Bruscia E, Allore H, Vander Wyk B, Tyagi A, Zeiss C. Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters. Viruses 2024, 16: 246. PMID: 38400021, PMCID: PMC10891789, DOI: 10.3390/v16020246.
De-labeling of Food Allergy in Electronic Medical Records for Cystic Fibrosis Patients to Avoid Unnecessary Food RestrictionNguyen H, Bruscia E, Young J, Egan M, Leeds S. De-labeling of Food Allergy in Electronic Medical Records for Cystic Fibrosis Patients to Avoid Unnecessary Food Restriction. Journal Of Allergy And Clinical Immunology 2024, 153: ab114. DOI: 10.1016/j.jaci.2023.11.376.
Appropriate Selection of Antihistamines in the Management of Allergic Reactions in the Pediatric Emergency Room: a quality improvement initiativeTepler E, Mehta M, Tiyyagura G, Goldman M, Powers E, Soffer G. Appropriate Selection of Antihistamines in the Management of Allergic Reactions in the Pediatric Emergency Room: a quality improvement initiative. Journal Of Allergy And Clinical Immunology 2024, 153: ab54. DOI: 10.1016/j.jaci.2023.11.192.
Exploring Factors for Implementation of EPAs in Pediatric Subspecialty Fellowships: A Qualitative Study of Program DirectorsCzaja A, Mink R, Herman B, Weiss P, Turner D, Curran M, Stafford D, Myers A, Langhan M. Exploring Factors for Implementation of EPAs in Pediatric Subspecialty Fellowships: A Qualitative Study of Program Directors. Journal Of Medical Education And Curricular Development 2024, 11: 23821205231225011. PMID: 38268726, PMCID: PMC10807342, DOI: 10.1177/23821205231225011.

2023

SOMETHING'S FISHY WITH THE FEED: AN IGE-MEDIATED ALLERGIC REACTION TO HUMAN MILKHalperin-Goldstein S, Soffer G. SOMETHING'S FISHY WITH THE FEED: AN IGE-MEDIATED ALLERGIC REACTION TO HUMAN MILK. Annals Of Allergy Asthma & Immunology 2023, 131: s170. DOI: 10.1016/j.anai.2023.08.523.
93 Persistent airway infections in cystic fibrosis–like mouse models correlate with phenotypic changes of clinical Pseudomonas aeruginosa isolatesOez H, Braga C, Laurence E, Gudneppanavar R, Huang P, Zhang P, Egan M, Bruscia E, Murray T. 93 Persistent airway infections in cystic fibrosis–like mouse models correlate with phenotypic changes of clinical Pseudomonas aeruginosa isolates. Journal Of Cystic Fibrosis 2023, 22: s48. DOI: 10.1016/s1569-1993(23)01028-7.
361 Chronic lung inflammation abrogates quiescent state of hematopoietic stem cells in a cystic fibrosis mouse modelBraga C, Mancuso R, Thompson E, Oez H, Gudneppanavar R, Zhang P, Huang P, Murray T, Egan M, Krause D, Bruscia E. 361 Chronic lung inflammation abrogates quiescent state of hematopoietic stem cells in a cystic fibrosis mouse model. Journal Of Cystic Fibrosis 2023, 22: s183. DOI: 10.1016/s1569-1993(23)01288-2.
220 Ezrin is required to maintain the number and function of tissue resident alveolar macrophages in cystic fibrosis during infectionGudneppanavar R, Di Pietro C, Oez H, Zhang P, Huang P, Britto-Leon C, Krause D, Egan M, Murray T, Bruscia E. 220 Ezrin is required to maintain the number and function of tissue resident alveolar macrophages in cystic fibrosis during infection. Journal Of Cystic Fibrosis 2023, 22: s113. DOI: 10.1016/s1569-1993(23)01150-5.
359 Distinct IL-10low IFN-γhigh signature is associated with IgG versus IgE response to peanut allergen exposure in CFTR–/– miceEmmenegger M, Hoyt L, Gudneppanavar R, Eisenbarth S, Egan M, Bruscia E, Aguzzi A. 359 Distinct IL-10low IFN-γhigh signature is associated with IgG versus IgE response to peanut allergen exposure in CFTR–/– mice. Journal Of Cystic Fibrosis 2023, 22: s182. DOI: 10.1016/s1569-1993(23)01286-9.
150 Optimizing workflowto understand the impact of CFTR dysfunction on airway immune cell transcriptomes in early disease pathogenesisKizilirmak T, Garrison A, Yin H, Bruscia E, Egan M, Britto-Leon C. 150 Optimizing workflowto understand the impact of CFTR dysfunction on airway immune cell transcriptomes in early disease pathogenesis. Journal Of Cystic Fibrosis 2023, 22: s79-s80. DOI: 10.1016/s1569-1993(23)01082-2.
276 Delivery of CFTR mRNA using polymeric nanoparticles in a cystic fibrosis mouse modelGarrison A, Suberi A, Browne J, Eaton D, Akhtar L, Kizilirmak T, Bruscia E, Piotrowski-Daspit A, Saltzman W, Egan M. 276 Delivery of CFTR mRNA using polymeric nanoparticles in a cystic fibrosis mouse model. Journal Of Cystic Fibrosis 2023, 22: s140. DOI: 10.1016/s1569-1993(23)01204-3.
194 Investigating the role of bromodomain-containing 8 isoforms in the innate immune response of human airway epithelial cellsBrowne J, Bruscia E, Garrison A, Harris A, Egan M. 194 Investigating the role of bromodomain-containing 8 isoforms in the innate immune response of human airway epithelial cells. Journal Of Cystic Fibrosis 2023, 22: s101. DOI: 10.1016/s1569-1993(23)01124-4.
378 CFTR modulator therapy prescription rates in the pediatric cystic fibrosis population: a decade of careBrumer E, Shabanova V, Rosano J, Mercurio M, Chen L, Sheares B, Egan M. 378 CFTR modulator therapy prescription rates in the pediatric cystic fibrosis population: a decade of care. Journal Of Cystic Fibrosis 2023, 22: s191-s192. DOI: 10.1016/s1569-1993(23)01305-x.
Diversity, Equity, and Inclusion in the Pediatric Pulmonary Workforce: An Official American Thoracic Society Workshop ReportStephenson N, Forno E, Laguna T, Lovinsky-Desir S, Moore P, Sheares B, Kazmerski T, Udoko M, Lypson M, Harding L, Wilkes D, Adair D, Afolabi F, Balasubramaniam V, Ale G, Castner L, Ghera P, Heras A, Jordan K, Ly N, Martinez-Fernandez T, Mishra P, Narang I, Palla J, Rivera-Sanchez Y, Tapia I, Toprak D, Torres-Silva C, Cohen R. Diversity, Equity, and Inclusion in the Pediatric Pulmonary Workforce: An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2023, 20: 1373-1388. PMID: 37772940, PMCID: PMC10559131, DOI: 10.1513/annalsats.202306-583st.
Early emergence of racial and ethnic differences in sleep health among toddlers living in low-income familiesOrdway M, Sadler L, Jeon S, Pierre J, Canapari C, Redeker N. Early emergence of racial and ethnic differences in sleep health among toddlers living in low-income families. Sleep Health 2023, 9: 389-397. PMID: 37453903, PMCID: PMC10517059, DOI: 10.1016/j.sleh.2023.02.006.
Improving Diversity, Equity, and Inclusion Content in Pediatrics Grand RoundsOstfeld-Johns S, Leverette D, Dioneda B, Malcolm J, Crittenden F, Carr C, Taylor A, Amaya K, Weiss P, Grossman M, Berkwitt A. Improving Diversity, Equity, and Inclusion Content in Pediatrics Grand Rounds. Academic Pediatrics 2023, 23: 1502-1504. PMID: 37321407, DOI: 10.1016/j.acap.2023.06.003.
Racial, Ethnic, and Socioeconomic Differences in Food Allergies in the USJiang J, Warren C, Brewer A, Soffer G, Gupta R. Racial, Ethnic, and Socioeconomic Differences in Food Allergies in the US. JAMA Network Open 2023, 6: e2318162. PMID: 37314805, PMCID: PMC10267771, DOI: 10.1001/jamanetworkopen.2023.18162.
The emerging role of child life specialists in the pediatric food allergy clinicMathew M, Stahl U, Soffer G. The emerging role of child life specialists in the pediatric food allergy clinic. Annals Of Allergy Asthma & Immunology 2023, 131: 296-297. PMID: 37209837, DOI: 10.1016/j.anai.2023.05.013.
Hemoptysis in the Time of COVIDKockar Kizilirmak T, Brumer E, Panacherry S, Egan M. Hemoptysis in the Time of COVID. 2023, a1928-a1928. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1928.
The effects of elexafactor/tezafactor/ivacaftor beyond the epithelium: spurring macrophages to fight infections.Bruscia E. The effects of elexafactor/tezafactor/ivacaftor beyond the epithelium: spurring macrophages to fight infections. European Respiratory Journal 2023, 61: 2300216. PMID: 37003613, DOI: 10.1183/13993003.00216-2023.
The Importance of Subspecialty Pediatricians to the Health and Well-Being of the Nation’s ChildrenMyers A, Fussell J, Moffatt M, Boyer D, Ross R, Dammann C, Degnon L, Weiss P, Sauer C, Vinci R. The Importance of Subspecialty Pediatricians to the Health and Well-Being of the Nation’s Children. The Journal Of Pediatrics 2023, 257: 113365. PMID: 36894130, DOI: 10.1016/j.jpeds.2023.02.011.
Moving toward standardization: physician reporting of sleep studies.Lastra A, Ingram D, Park J, James E, Matthews C, Canapari C, Mansukhani M, Stahl S. Moving toward standardization: physician reporting of sleep studies. Journal Of Clinical Sleep Medicine 2023, 19: 595-603. PMID: 36546360, PMCID: PMC9978423, DOI: 10.5664/jcsm.10442.
Future therapies for cystic fibrosisAllen L, Allen L, Carr S, Davies G, Downey D, Egan M, Forton J, Gray R, Haworth C, Horsley A, Smyth A, Southern K, Davies J. Future therapies for cystic fibrosis. Nature Communications 2023, 14: 693. PMID: 36755044, PMCID: PMC9907205, DOI: 10.1038/s41467-023-36244-2.
Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapyKaman K, Dhodapkar M, Shabanova V, McCollum S, Factor J, Leeds S. Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy. Annals Of Allergy Asthma & Immunology 2023, 130: 657-663. PMID: 36738780, DOI: 10.1016/j.anai.2023.01.028.
Paired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility StudyWi C, Gent J, Bublitz J, King K, Ryu E, Sorrentino K, Plano J, McKay L, Porcher J, Wheeler P, Chiarella S, DeWan A, Pollitt K, Sheares B, Leaderer B, Juhn Y. Paired Indoor and Outdoor Nitrogen Dioxide Associated With Childhood Asthma Outcomes in a Mixed Rural-Urban Setting: A Feasibility Study. Journal Of Primary Care & Community Health 2023, 14: 21501319231173813. PMID: 37243352, PMCID: PMC10226331, DOI: 10.1177/21501319231173813.
Parent-reported penicillin allergies in children: A qualitative study.Carter EJ, Kaman K, Baron K, Miller M, Krol DM, Harpalani D, Aseltine RH, Pagoto S. Parent-reported penicillin allergies in children: A qualitative study. Am J Infect Control 2023, 51: 56-61. PMID: 35537563, DOI: 10.1016/j.ajic.2022.04.008.

2022

Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsiesMaskey A, Wang Z, Chen X, Dunkin D, Yang N, Soffer G, Yuan Q, Li X. Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies. Frontiers In Immunology 2022, 13: 1015437. PMID: 36591238, PMCID: PMC9797535, DOI: 10.3389/fimmu.2022.1015437.
Update on Innate and Adaptive Immunity in Cystic FibrosisBruscia E, Bonfield T. Update on Innate and Adaptive Immunity in Cystic Fibrosis. Clinics In Chest Medicine 2022, 43: 603-615. PMID: 36344069, DOI: 10.1016/j.ccm.2022.06.004.
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosisÖz H, Cheng E, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang P, Huang P, Esquibies S, Britto C, Schupp J, Murray T, Halene S, Krause D, Egan M, Bruscia E. Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis. Cell Reports 2022, 41: 111797. PMID: 36516754, PMCID: PMC9833830, DOI: 10.1016/j.celrep.2022.111797.
Non-Modulator Therapies Developing a Therapy for Every Cystic Fibrosis PatientEgan M. Non-Modulator Therapies Developing a Therapy for Every Cystic Fibrosis Patient. Clinics In Chest Medicine 2022, 43: 717-725. PMID: 36344076, DOI: 10.1016/j.ccm.2022.06.011.
Clinical competency committee perceptions of entrustable professional activities and their value in assessing fellows: A qualitative study of pediatric subspecialty program directorsLanghan M, Stafford D, Myers A, Herman B, Curran M, Czaja A, Turner D, Weiss P, Mink R. Clinical competency committee perceptions of entrustable professional activities and their value in assessing fellows: A qualitative study of pediatric subspecialty program directors. Medical Teacher 2022, 45: 650-657. PMID: 36420760, DOI: 10.1080/0142159x.2022.2147054.
Human neutrophil development and functionality are enabled in a humanized mouse modelZheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Human neutrophil development and functionality are enabled in a humanized mouse model. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2121077119. PMID: 36269862, PMCID: PMC9618085, DOI: 10.1073/pnas.2121077119.
In vivo correction of cystic fibrosis mediated by PNA nanoparticlesPiotrowski-Daspit AS, Barone C, Lin CY, Deng Y, Wu D, Binns TC, Xu E, Ricciardi AS, Putman R, Garrison A, Nguyen R, Gupta A, Fan R, Glazer PM, Saltzman WM, Egan ME. In vivo correction of cystic fibrosis mediated by PNA nanoparticles. Science Advances 2022, 8: eabo0522. PMID: 36197984, PMCID: PMC9534507, DOI: 10.1126/sciadv.abo0522.
Defining socioeconomic and racial disparities in food allergy: The time is now.Leeds S, Nowak-Wegrzyn A. Defining socioeconomic and racial disparities in food allergy: The time is now. Annals Of Allergy, Asthma & Immunology : Official Publication Of The American College Of Allergy, Asthma, & Immunology 2022, 129: 391-392. PMID: 36155692, DOI: 10.1016/j.anai.2022.07.018.
455 Impaired recruitment of C-C motif chemokine receptor 2-positive monocytes does not compromise host defense against pulmonary Pseudomonas aeruginosa infectionsÖz H, Di Pietro C, Rodrigues G, Zhang P, Huang P, Egan M, Murray T, Bruscia E. 455 Impaired recruitment of C-C motif chemokine receptor 2-positive monocytes does not compromise host defense against pulmonary Pseudomonas aeruginosa infections. Journal Of Cystic Fibrosis 2022, 21: s260. DOI: 10.1016/s1569-1993(22)01145-6.
674 Loss of functional cystic fibrosis transmembrane conductance regulator leads to a calpain-dependent degradation of ezrin in activated cystic fibrosis macrophagesDi Pietro C, Öz H, Rodrigues G, Huang P, Zhang P, Murray T, Egan M, Bruscia E. 674 Loss of functional cystic fibrosis transmembrane conductance regulator leads to a calpain-dependent degradation of ezrin in activated cystic fibrosis macrophages. Journal Of Cystic Fibrosis 2022, 21: s369. DOI: 10.1016/s1569-1993(22)01364-9.
491 Pel overexpression by Pseudomonas aeruginosa reduces induction of heme-oxygenase 1 in macrophagesRodrigues G, Di Pietro C, Huang P, Öz H, Bruscia E, Murray T. 491 Pel overexpression by Pseudomonas aeruginosa reduces induction of heme-oxygenase 1 in macrophages. Journal Of Cystic Fibrosis 2022, 21: s278. DOI: 10.1016/s1569-1993(22)01181-x.
Safety Considerations for Natural Products Commonly Used By Patients with Allergic DiseaseSoffer G, Shroff P, Horwitz R. Safety Considerations for Natural Products Commonly Used By Patients with Allergic Disease. The Journal Of Allergy And Clinical Immunology In Practice 2022, 10: 3131-3138. PMID: 36174919, DOI: 10.1016/j.jaip.2022.09.025.
Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible MiceMaskey A, Srivastava K, Soffer G, Dunkin D, Yuan Q, Li X. Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice. Journal Of Inflammation Research 2022, 15: 5527-5540. PMID: 36176352, PMCID: PMC9514888, DOI: 10.2147/jir.s372449.
Admitting what is needed: How the health system and society can reduce hospitalizations for children with medical complexity.Chen LP, Gerber DM, Coller RJ. Admitting what is needed: How the health system and society can reduce hospitalizations for children with medical complexity. Journal Of Hospital Medicine 2022 PMID: 35996947, DOI: 10.1002/jhm.12948.
Emerging Concepts in Defective Macrophage Phagocytosis in Cystic FibrosisJaganathan D, Bruscia EM, Kopp BT. Emerging Concepts in Defective Macrophage Phagocytosis in Cystic Fibrosis. International Journal Of Molecular Sciences 2022, 23: 7750. PMID: 35887098, PMCID: PMC9319215, DOI: 10.3390/ijms23147750.
Gene therapy applications to transfusion medicineTabibi S, Gehrie E, Bruscia E, Krause D. Gene therapy applications to transfusion medicine. 2022, 642-647. DOI: 10.1002/9781119719809.ch56.
Cutaneous epitheliotropic lymphosarcoma in a captive white catfish (Ameiurus catus Linnaeus).Heniff AC, Chen LR, Christiansen EF, Harms CA, Law JM, Legner C, Linder KE. Cutaneous epitheliotropic lymphosarcoma in a captive white catfish (Ameiurus catus Linnaeus). Journal Of Fish Diseases 2022, 45: 971-974. PMID: 35475494, PMCID: PMC9320794, DOI: 10.1111/jfd.13625.
Associations between sleep problems and domains relevant to daytime functioning and clinical symptomatology in autism: A meta‐analysisHan GT, Trevisan DA, Abel EA, Cummings EM, Carlos C, Bagdasarov A, Kala S, Parker T, Canapari C, McPartland JC. Associations between sleep problems and domains relevant to daytime functioning and clinical symptomatology in autism: A meta‐analysis. Autism Research 2022, 15: 1249-1260. PMID: 35635067, DOI: 10.1002/aur.2758.
0847 Sleep Disordered Breathing in a case series of 4 children with Trisomy 18Kochhar R, Brumer E, Canapari C. 0847 Sleep Disordered Breathing in a case series of 4 children with Trisomy 18. Sleep 2022, 45: a364-a365. DOI: 10.1093/sleep/zsac079.841.
Ensuring Timely Pulmonary Follow Up After an Inpatient Asthma Hospitalization: A Quality Improvement InitiativeBrumer E, Cherian C, Godse S, Kockar Kizilirmak T, Grossman M, Chen L, Sheares B. Ensuring Timely Pulmonary Follow Up After an Inpatient Asthma Hospitalization: A Quality Improvement Initiative. 2022, a5722-a5722. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5722.
Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosisDi Pietro C, Öz HH, Zhang PX, Cheng EC, Martis V, Bonfield TL, Kelley TJ, Jubin R, Abuchowski A, Krause DS, Egan ME, Murray TS, Bruscia EM. Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis. Experimental & Molecular Medicine 2022, 54: 639-652. PMID: 35581352, PMCID: PMC9166813, DOI: 10.1038/s12276-022-00770-8.
Association of fractional exhaled nitric oxide with asthma morbidity in urban minority children.Chen L, Agalliu I, Roth A, Rastogi D. Association of fractional exhaled nitric oxide with asthma morbidity in urban minority children. The Journal Of Asthma : Official Journal Of The Association For The Care Of Asthma 2022, 1-12. PMID: 35499408, DOI: 10.1080/02770903.2022.2073549.
A Flavonoid Compound 7, 4 Dihydroxy Flavone as a Potential Therapeutic for the Treatment and Management of EoEMaskey A, Wang Z, Chen X, Dunkin D, Soffer G, Yuan Q, Li X. A Flavonoid Compound 7, 4 Dihydroxy Flavone as a Potential Therapeutic for the Treatment and Management of EoE. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r4598.
Health disparities in pediatric food allergyTepler E, Wong KH, Soffer GK. Health disparities in pediatric food allergy. Annals Of Allergy Asthma & Immunology 2022, 129: 417-423. PMID: 35476967, DOI: 10.1016/j.anai.2022.04.022.
Characteristics and prevalence of antibiotic allergies in patients with sickle cell disease: A single‐center retrospective studyWong KH, Soffer GK. Characteristics and prevalence of antibiotic allergies in patients with sickle cell disease: A single‐center retrospective study. American Journal Of Hematology 2022, 97: e247-e249. PMID: 35358357, DOI: 10.1002/ajh.26555.
Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cellsLuks VL, Mandl H, DiRito J, Barone C, Freedman-Weiss MR, Ricciardi AS, Tietjen GG, Egan ME, Saltzman WM, Stitelman DH. Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells. PLOS ONE 2022, 17: e0266218. PMID: 35385514, PMCID: PMC8986008, DOI: 10.1371/journal.pone.0266218.
Clinical experience with sesame oral immunotherapy and a quality-of-life assessmentYou L, Soffer G, Factor J. Clinical experience with sesame oral immunotherapy and a quality-of-life assessment. Journal Of Food Allergy 2022, 4: 1-9. PMID: 39021386, PMCID: PMC11250642, DOI: 10.2500/jfa.2022.4.220003.
Peripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic EsophagitisShin J, Kaman K, Anthonypillai J, Soffer G, Kang I. Peripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic Esophagitis. Journal Of Allergy And Clinical Immunology 2022, 149: ab204. DOI: 10.1016/j.jaci.2021.12.670.
IgE Independent Induction of EoE by Airborne Antigens via Up-regulation of Th2 ResponsesMaskey A, Srivastava K, Soffer G, Dunkin D, Yuan Q, Li X. IgE Independent Induction of EoE by Airborne Antigens via Up-regulation of Th2 Responses. Journal Of Allergy And Clinical Immunology 2022, 149: ab202. DOI: 10.1016/j.jaci.2021.12.665.
Scholarly activity training in pediatric pulmonology fellowship programsWeiss P, Rama J, Gerber LM, Qiu Y, Li S, Duncan JG, Naifeh MM, Stevenson MD, Mauer E, Abramson EL. Scholarly activity training in pediatric pulmonology fellowship programs. Pediatric Pulmonology 2022, 57: 982-990. PMID: 35018735, DOI: 10.1002/ppul.25815.
Addressing Mistreatment of Providers by Patients and Family Members as a Patient Safety Event.Hatfield M, Ciaburri R, Shaikh H, Wilkins KM, Bjorkman K, Goldenberg M, McCollum S, Shabanova V, Weiss P. Addressing Mistreatment of Providers by Patients and Family Members as a Patient Safety Event. Hospital Pediatrics 2022, 12: 181-190. PMID: 35102377, DOI: 10.1542/hpeds.2021-006267.
A practical focus on sesame allergy and a brief review of other seed allergiesKaman, K. Factor, J. A practical focus on sesame allergy and a brief review of other seed aller-gies. Journal of Food Allergy. July 2022.
Peripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic Esophagitis. Shin, J. Kaman, K. Anthonypillai, J. Soffer, G. Kang, I. (2022). Peripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic Esophagitis. Journal of Allergy and Clinical Immunology. February 2022.

2021

Fellow Entrustment for the Common Pediatric Subspecialty Entrustable Professional Activities Across SubspecialtiesPitts S, Schwartz A, Carraccio CL, Herman BE, Mahan JD, Sauer CG, Dammann CEL, Aye T, Myers AL, Weiss PG, Turner DA, Hsu DC, Stafford DEJ, Chess PR, Fussell JJ, McGann KA, High P, Curran ML, Mink RB. Fellow Entrustment for the Common Pediatric Subspecialty Entrustable Professional Activities Across Subspecialties. Academic Pediatrics 2021, 22: 881-886. PMID: 34936942, DOI: 10.1016/j.acap.2021.12.019.
A Clinical Guide to Pediatric Sleep: Diagnosis and Management of Sleep Problems, Third Edition Jodi A. Mindell Judith A. Owens A Clinical Guide to Pediatric Sleep: Diagnosis and Management of Sleep Problems Third Edition 2015 Wolters Kluwer Philadelphia, PABaddam S, Nasser A. A Clinical Guide to Pediatric Sleep: Diagnosis and Management of Sleep Problems, Third Edition Jodi A. Mindell Judith A. Owens A Clinical Guide to Pediatric Sleep: Diagnosis and Management of Sleep Problems Third Edition 2015 Wolters Kluwer Philadelphia, PA. Journal Of The American Academy Of Child & Adolescent Psychiatry 2021, 60: 1536-1538. DOI: 10.1016/j.jaac.2021.10.005.
Achieving Entrustable Professional Activities During FellowshipWeiss PG, Schwartz A, Carraccio CL, Herman BE, Turner DA, Aye T, Fussell JJ, Kesselheim J, Mahan JD, McGann KA, Myers A, Stafford DEJ, Chess PR, Curran ML, Dammann CEL, High P, Hsu DC, Pitts S, Sauer C, Srivastava S, Mink RB. Achieving Entrustable Professional Activities During Fellowship. Pediatrics 2021, 148: e2021050196. PMID: 34667096, DOI: 10.1542/peds.2021-050196.
558: Carbon monoxide–based therapy primes macrophages to express HO-1 and to resolve lung hyper-inflammation in cystic fibrosisPietro C, Öz H, Zhang P, Cheng E, Martis V, Bonfield T, Kelley T, Jubin R, Abuchowski A, Krause D, Egan M, Murray T, Bruscia E. 558: Carbon monoxide–based therapy primes macrophages to express HO-1 and to resolve lung hyper-inflammation in cystic fibrosis. Journal Of Cystic Fibrosis 2021, 20: s263-s264. DOI: 10.1016/s1569-1993(21)01981-0.
398: Host and pathogens contribute to decreased host defense protein SPLUNC1 in cystic fibrosisZielonka J, Khanal S, Webster M, Shiner N, Carpio A, Tarran R, Sharma L, DelaCruz C, Egan M, Britto C. 398: Host and pathogens contribute to decreased host defense protein SPLUNC1 in cystic fibrosis. Journal Of Cystic Fibrosis 2021, 20: s188. DOI: 10.1016/s1569-1993(21)01822-1.
473: Impairing the recruitment of inflammatory monocytes to CF lungs does not weaken host defense against pulmonary Pseudomonas aeruginosa infectionsÖz H, Di Pietro C, Cheng E, Zhang P, Huang P, Murray T, Egan M, Bruscia E. 473: Impairing the recruitment of inflammatory monocytes to CF lungs does not weaken host defense against pulmonary Pseudomonas aeruginosa infections. Journal Of Cystic Fibrosis 2021, 20: s223. DOI: 10.1016/s1569-1993(21)01897-x.
582: In vivo nanoparticle-mediated therapeutic nucleic acid delivery for CF treatmentPiotrowski-Daspit A, Bracaglia L, Barone C, Nguyen R, Glazer P, Egan M, Saltzman W. 582: In vivo nanoparticle-mediated therapeutic nucleic acid delivery for CF treatment. Journal Of Cystic Fibrosis 2021, 20: s277. DOI: 10.1016/s1569-1993(21)02005-1.
The immunologic response to severe acute respiratory syndrome coronavirus 2.Le NK, Kaman K, Martin HC, Mullur J, Stenehjem KK, Coomar L, Bahar B, Dutta M, Izurieta R, Brooks JP. The immunologic response to severe acute respiratory syndrome coronavirus 2. Allergy Asthma Proc 2021, 42: 495-505. PMID: 34871157, DOI: 10.2500/aap.2021.42.210077.
Mistreatment of Providers by Patients and Family Members: Effect of an Organizational Strategy on Provider Knowledge, Self-Efficacy, and Patient Safety Incident Reporting of MistreatmentWeiss PG, Hatfield M, Ciaburri R, Shaikh H, Wilkins KM, Bjorkman K, Goldenberg M, McCollum S, Shabanova V. Mistreatment of Providers by Patients and Family Members: Effect of an Organizational Strategy on Provider Knowledge, Self-Efficacy, and Patient Safety Incident Reporting of Mistreatment. Academic Medicine 2021, 96: s217-s218. PMID: 34705720, DOI: 10.1097/acm.0000000000004279.
A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing ImmunologistWong KH, Shapiro ED, Soffer GK. A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist. Clinical Reviews In Allergy & Immunology 2021, 62: 264-271. PMID: 34687445, DOI: 10.1007/s12016-021-08906-w.
Minimum Supervision Levels Required by Program Directors for Pediatric Pulmonary Fellow GraduationWeiss P, Schwartz A, Carraccio C, Herman BE, Mink RB. Minimum Supervision Levels Required by Program Directors for Pediatric Pulmonary Fellow Graduation. ATS Scholar 2021, 2: 360-369. PMID: 34667986, PMCID: PMC8519336, DOI: 10.34197/ats-scholar.2021-0013oc.
Current Fellowship Funding Limitations and Their Threat to the Pediatric Subspecialty WorkforceWeiss P, Myers AL, McGann KA, Kesselheim JC, Barron C, Klasner A, Heyman MB, Weiss DL, Mauer E, Mason KE, Gerber LM, Abramson EL. Current Fellowship Funding Limitations and Their Threat to the Pediatric Subspecialty Workforce. Academic Pediatrics 2021, 21: 1328-1330. PMID: 34389517, DOI: 10.1016/j.acap.2021.08.006.
Physician-Scientist Training and Programming in Pediatric Residency Programs: A National SurveyBurns AM, Moore DJ, Forster CS, Powell W, Thammasitboon S, Hostetter MK, Weiss P, Boyer D, Ward MA, Blankenburg R, Heyman MB, Rassbach CE, McPhillips H, French A, Nguyen S, Byrne BJ, Parsons DW, Gonzalez F, Nowalk AJ, Ho J, Kumar S, Orange JS, Ackerman KG. Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey. The Journal Of Pediatrics 2021, 241: 5-9.e3. PMID: 34280401, DOI: 10.1016/j.jpeds.2021.07.014.

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