2023
1-Year Outcomes in a Pooled Cohort of Harmony Transcatheter Pulmonary Valve Clinical Trial Participants
Gillespie M, McElhinney D, Jones T, Levi D, Asnes J, Gray R, Cabalka A, Fujimoto K, Qureshi A, Justino H, Bergersen L, Benson L, Haugan D, Boe B, Cheatham J. 1-Year Outcomes in a Pooled Cohort of Harmony Transcatheter Pulmonary Valve Clinical Trial Participants. JACC Cardiovascular Interventions 2023, 16: 1917-1928. PMID: 37278682, DOI: 10.1016/j.jcin.2023.03.002.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valveRight ventricular outflow tractSevere pulmonary regurgitationPulmonary regurgitationPrimary analysisCardiac magnetic resonance imagingContinued Access StudyMild pulmonary regurgitationOne-year safetyMedian patient agePulmonary valve replacementLong-term valve performanceVentricular outflow tractFirst U.S. FoodClinical trial participantsMagnetic resonance imagingEligible patientsMost patientsPatient ageValve replacementHemodynamic outcomesPooled cohortPulmonary valveVentricular tachycardiaClinical indications
2020
Transcatheter Pulmonary Valve Replacement With the Sapien Prosthesis
Shahanavaz S, Zahn EM, Levi DS, Aboulhousn JA, Hascoet S, Qureshi AM, Porras D, Morgan GJ, Bauser Heaton H, Martin MH, Keeshan B, Asnes JD, Kenny D, Ringewald JM, Zablah JE, Ivy M, Morray BH, Torres AJ, Berman DP, Gillespie MJ, Chaszczewski K, Zampi JD, Walsh KP, Julien P, Goldstein BH, Sathanandam SK, Karsenty C, Balzer DT, McElhinney DB. Transcatheter Pulmonary Valve Replacement With the Sapien Prosthesis. Journal Of The American College Of Cardiology 2020, 76: 2847-2858. PMID: 33303074, DOI: 10.1016/j.jacc.2020.10.041.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve replacementPulmonary valve replacementSAPIEN XTValve replacementS3 valveMost patientsShort-term outcome dataGreater pulmonary regurgitationMaximum Doppler gradientOutflow tract anatomyTricuspid valve injurySAPIEN 3 valveSerious adverse eventsBalloon-expandable valveShort-term outcomesSurgical valve replacementValve complicationsMulticenter registryUrgent surgeryAdverse eventsDoppler gradientPulmonary regurgitationSAPIEN prosthesisTotal patientsValve injury
2018
Initial results from the off‐label use of the SAPIEN S3 valve for percutaneous transcatheter pulmonary valve replacement: A multi‐institutional experience
Sinha S, Aboulhosn J, Asnes J, Bocks M, Zahn E, Goldstein BH, Zampi J, Hellenbrand W, Salem M, Levi D. Initial results from the off‐label use of the SAPIEN S3 valve for percutaneous transcatheter pulmonary valve replacement: A multi‐institutional experience. Catheterization And Cardiovascular Interventions 2018, 93: 455-463. PMID: 30537348, DOI: 10.1002/ccd.27973.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBalloon ValvuloplastyCardiac CatheterizationCardiac Surgical ProceduresChildFemaleHeart Defects, CongenitalHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMalePostoperative ComplicationsProsthesis DesignPulmonary ValvePulmonary Valve InsufficiencyRecovery of FunctionRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsTranscatheter pulmonary valve replacementRight ventricular outflow tractDysfunctional right ventricular outflow tractsSapien S3 valvePercutaneous transcatheter pulmonary valve replacementCongenital heart diseaseTricuspid valve injuryPulmonary valve replacementS3 valveSAPIEN S3Valve injuryValve replacementNative right ventricular outflow tractSerious procedural complicationsVentricular outflow tractMulti-center experienceMulti-institutional experienceOff-label useShort-term resultsAortic compressionValve embolizationPerivalvular leakProcedural deathsClinical followMajor complicationsIntentional Fracture of Bioprosthetic Valve Frames in Patients Undergoing Valve-in-Valve Transcatheter Pulmonary Valve Replacement
Shahanavaz S, Asnes JD, Grohmann J, Qureshi AM, Rome JJ, Tanase D, Crystal MA, Latson LA, Morray BH, Hellenbrand W, Balzer DT, Gewillig M, Love JC, Berdjis F, Gillespie MJ, McElhinney DB. Intentional Fracture of Bioprosthetic Valve Frames in Patients Undergoing Valve-in-Valve Transcatheter Pulmonary Valve Replacement. Circulation Cardiovascular Interventions 2018, 11: e006453. PMID: 30354783, DOI: 10.1161/circinterventions.118.006453.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBioprosthesisCardiac CatheterizationChildFeasibility StudiesFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHemodynamicsHumansMaleMiddle AgedPreliminary DataProsthesis DesignProsthesis FailurePulmonary ValveRecovery of FunctionRetrospective StudiesTime FactorsTreatment OutcomeYoung AdultConceptsTranscatheter pulmonary valve replacementPulmonary valve replacementBioprosthetic valvesValve replacementPercutaneous transcatheter pulmonary valve replacementRight ventricular outflow tract gradientVentricular outflow tract gradientDysfunctional bioprosthetic valvePulmonary valve orificeOutflow tract gradientPatient-prosthesis mismatchIntentional fractureTrue inner diameterMedian 40Tract gradientMelody valveSAPIEN valveAdverse eventsHemodynamic outcomesValve therapyFracture groupPeak gradientControl cohortPulmonary positionBetter hemodynamicsTranscatheter Pulmonary Valve Replacement With the Melody Valve in Small Diameter Expandable Right Ventricular Outflow Tract Conduits
Shahanavaz S, Qureshi AM, Levi DS, Boudjemline Y, Peng LF, Martin MH, Bauser-Heaton H, Keeshan B, Asnes JD, Jones TK, Justino H, Aboulhosn JA, Gray RG, Nguyen H, Balzer DT, McElhinney DB. Transcatheter Pulmonary Valve Replacement With the Melody Valve in Small Diameter Expandable Right Ventricular Outflow Tract Conduits. JACC Cardiovascular Interventions 2018, 11: 554-564. PMID: 29566801, DOI: 10.1016/j.jcin.2018.01.239.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAngiographyBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationCardiac CatheterizationChildChild, PreschoolFeasibility StudiesFemaleGraft Occlusion, VascularHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHemodynamicsHumansMalePreliminary DataProsthesis DesignPulmonary ValveRetrospective StudiesTime FactorsTreatment OutcomeUnited StatesVentricular Outflow ObstructionYoung AdultConceptsTranscatheter pulmonary valve replacementRight ventricular outflow tractPulmonary valve replacementMelody valveValve replacementDysfunctional right ventricular outflow tractsPercutaneous transcatheter pulmonary valve replacementSuccessful transcatheter pulmonary valve replacementSignificant hemodynamic improvementSignificant pulmonary regurgitationVentricular outflow tractCases of endocarditisRVOT reinterventionHemodynamic improvementPulmonary regurgitationHemodynamic outcomesOutflow tractProcedural characteristicsPreliminary experiencePatientsSmall diameter conduitsLimited dataOutcomesSmall conduitsReintervention
2017
Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern?
Simmons MA, Elder RW, Shabanova V, Hellenbrand W, Asnes J. Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern? Catheterization And Cardiovascular Interventions 2017, 91: 920-926. PMID: 29280541, DOI: 10.1002/ccd.27454.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve implantationRight ventricular outflow tractNative outflow tractsSignificant ventricular arrhythmiasPulmonary valve implantationVentricular arrhythmiasOutflow tractValve implantationAnti-arrhythmic medicationsBeta-blocker therapySingle-center studyVentricular outflow tractLong-term therapySudden cardiac deathCare of patientsChange of doseHemodynamic instabilityHemodynamic compromiseCardiac deathMedian ageMedical therapyPediatric patientsSignificant arrhythmiasCenter studyTerm therapyTranscatheter pulmonary valve replacement using the melody valve for treatment of dysfunctional surgical bioprostheses: A multicenter study
Cabalka AK, Asnes JD, Balzer DT, Cheatham JP, Gillespie MJ, Jones TK, Justino H, Kim DW, Lung TH, Turner DR, McElhinney DB. Transcatheter pulmonary valve replacement using the melody valve for treatment of dysfunctional surgical bioprostheses: A multicenter study. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 1712-1724.e1. PMID: 29395214, DOI: 10.1016/j.jtcvs.2017.10.143.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBioprosthesisCardiac CatheterizationChildChild, PreschoolFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedProsthesis DesignProsthesis FailurePulmonary ValvePulmonary Valve InsufficiencyPulmonary Valve StenosisRecovery of FunctionRetrospective StudiesTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsPulmonary valve replacementTPV replacementPulmonary regurgitationBioprosthetic valvesValve replacementMulticenter studyRight ventricular outflow tract gradientPostoperative congenital heart diseaseTranscatheter pulmonary valve replacementVentricular outflow tract gradientSurgical pulmonary valve replacementMean RVOT gradientMedian patient ageOutflow tract gradientSevere pulmonary regurgitationExcellent early resultsSurgical bioprosthetic valvesTetralogy of FallotCongenital heart diseaseTime-related fashionRVOT gradientTract gradientUnderlying diagnosisHospital dischargePatient agePercutaneous transcatheter pulmonary valve replacement in children weighing less than 20 kg
Martin MH, Shahanavaz S, Peng LF, Asnes JD, Riley M, Hellenbrand WE, Balzer DT, Gray RG, McElhinney DB. Percutaneous transcatheter pulmonary valve replacement in children weighing less than 20 kg. Catheterization And Cardiovascular Interventions 2017, 91: 485-494. PMID: 29193671, DOI: 10.1002/ccd.27432.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBody WeightCardiac CatheterizationChildChild DevelopmentChild, PreschoolCoronary AngiographyEchocardiography, DopplerFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMalePostoperative ComplicationsPulmonary ValveRetrospective StudiesRisk FactorsTreatment OutcomeUnited StatesConceptsTranscatheter pulmonary valve replacementPercutaneous transcatheter pulmonary valve replacementPulmonary valve replacementTetralogy of FallotValve replacementVein accessInternal jugular vein accessExcellent valve functionMean Doppler gradientMild pulmonary regurgitationIliac vein injuryCases of endocarditisFemoral vein accessSuccessful valve implantationJugular vein accessIJV accessRVOT reinterventionMelody valveAdverse eventsDoppler gradientPulmonary regurgitationValve implantationMedian ageVein injuryRoot compressionComparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement
Li WF, Pollard H, Karimi M, Asnes JD, Hellenbrand WE, Shabanova V, Weismann CG. Comparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement. Congenital Heart Disease 2017, 13: 140-146. PMID: 29148206, PMCID: PMC5796854, DOI: 10.1111/chd.12544.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBioprosthesisCardiac CatheterizationChildChild, PreschoolEchocardiographyFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHeart VentriclesHumansMaleMiddle AgedPulmonary ValvePulmonary Valve InsufficiencyRetrospective StudiesTime FactorsTreatment OutcomeVentricular Function, RightVentricular RemodelingYoung AdultConceptsRight ventricular outflow tract obstructionPulmonary valve replacementSurgical pulmonary valve replacementRight ventricular functionPulmonic insufficiencyVentricular functionTC groupRV functionSurgical groupValve replacementRV sizeVentricular outflow tract obstructionYale-New Haven HospitalOutflow tract obstructionTract obstructionPatient ageRetrospective reviewSurgical valvesPostoperative declinePulmonary valveHigh riskValve functionPatientsFirst choiceTime points
2015
Evaluation of the Melody transcatheter pulmonary valve and Ensemble delivery system for the treatment of dysfunctional right ventricle to pulmonary artery conduits
Asnes J, Hellenbrand WE. Evaluation of the Melody transcatheter pulmonary valve and Ensemble delivery system for the treatment of dysfunctional right ventricle to pulmonary artery conduits. Expert Review Of Medical Devices 2015, 12: 653-665. PMID: 26513599, DOI: 10.1586/17434440.2015.1102050.Peer-Reviewed Original ResearchConceptsMelody transcatheter pulmonary valveTranscatheter pulmonary valvePulmonary valveValve functionPercutaneous transcatheter pulmonary valve replacementTranscatheter pulmonary valve replacementRight ventricular outflow tractPulmonary valve replacementRight heart failurePulmonary artery conduitRelief of obstructionVentricular outflow tractDysfunctional right ventricleOpen heart surgeryRecent clinical trialsTreatment of patientsCongenital heart diseaseArtery conduitValve replacementConduit dysfunctionHeart failureConduit functionHeart diseaseRight ventricleClinical trials