2023
Identification of a Novel Gene Regulatory Element in Human Erythroid Progenitor Cells
Schulz V, Lezon-Geyda K, Shan P, Papoin J, Narla M, Steiner L, Blanc L, Palis J, Gallagher P. Identification of a Novel Gene Regulatory Element in Human Erythroid Progenitor Cells. Blood 2023, 142: 9. DOI: 10.1182/blood-2023-186046.Peer-Reviewed Original ResearchErythroid progenitor cellsActive enhancersEarly erythropoiesisChIP-seqRegulatory elementsGene expressionATAC-seqRUNX motifsGATA motifSingle nucleotide polymorphismsProgenitor cellsGATA1 bindingDisease genesEnhancer regionErythroid lineageTissue-specific transcription factorsNovel gene regulatory elementsNovel enhancer regionErythrocyte traitsGenome-wide association studiesDirect tissue-specific expressionNovel regulatory elementGene regulatory elementsHuman erythroid progenitor cellsTerminal erythroid differentiation
2009
Genome Expression Profiling of the First Hematopoietic Progenitors of the Mouse Embryo.
Baron M, Isern J, Fraser S, He Z, Tuck D, Schulz V, Gallagher P. Genome Expression Profiling of the First Hematopoietic Progenitors of the Mouse Embryo. Blood 2009, 114: 2536. DOI: 10.1182/blood.v114.22.2536.2536.Peer-Reviewed Original ResearchGenome expression profilingMouse embryosGFP reporterExpression profilingErythroid lineageLineage-specific cell typesEmbryonic globin genesDefinitive erythroid lineagesHematopoietic progenitorsGlobin gene expressionCandidate transcriptional regulatorsCell typesPrimitive erythroid lineageLineage-specific expressionEarly mouse embryosAnalysis of promotersEnd of gastrulationEmbryonic day 7.5Hematopoietic cell typesEarly hematopoietic progenitorsExpression of GATA2Distinct functional classesOrganelle biogenesisRibosome biogenesisPrimitive erythropoiesis