2002
Biological significance of insulin-like growth factor binding proteins
Weinzimer S, Cohen P. Biological significance of insulin-like growth factor binding proteins. NeuroImmune Biology 2002, 2: 37-65. DOI: 10.1016/s1567-7443(02)80007-2.Peer-Reviewed Original ResearchInsulin-like growth factorGrowth factorFree insulin-like growth factorIGF/IGFBP axisCleavage of IGFBPsIGF-dependent actionsIGF-independent actionsPotent mitogenic agentsIGFBP axisIGFBP proteasesIGF receptorInflammatory diseasesIGFBPsGrowth disordersMitogenic agentsCellular proliferationCell growthSomatic growthHigh affinityPathophysiologyCancerProteinFactorsDiseaseBiological significance
2001
Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein1
Weinzimer S, Gibson T, Collett-Solberg P, Khare A, Liu B, Cohen P. Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein1. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 1806-1813. PMID: 11297622, DOI: 10.1210/jcem.86.4.7380.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsApoptosisCarrier ProteinsCell DivisionCells, CulturedDose-Response Relationship, DrugFluorescent Antibody TechniqueHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding ProteinsIronKineticsMaleMicroscopy, ConfocalMuscle, SmoothProstatic NeoplasmsSheepTissue DistributionTransferrinUrinary BladderYeastsConceptsIGFBP-3IGFBP-3-induced apoptosisInsulin-like growth factorBladder smooth muscle cellsHuman liver complementary DNA libraryProstate cancer cellsSmooth muscle cellsImportant physiological effectsIGF actionBinding proteinProteins/receptorsMuscle cellsProtein 3Growth factorCancer cellsCell proliferationTF treatmentPhysiological effectsNegligible affinityHuman serumTransferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein
Weinzimer SA. Transferrin Is an Insulin-Like Growth Factor-Binding Protein-3 Binding Protein. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 1806-1813. DOI: 10.1210/jc.86.4.1806.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsApoptosisCarrier ProteinsCell DivisionCells, CulturedDose-Response Relationship, DrugFluorescent Antibody TechniqueHumansInsulin-Like Growth Factor Binding Protein 3Insulin-Like Growth Factor Binding ProteinsIronKineticsMaleMicroscopy, ConfocalMuscle, SmoothProstatic NeoplasmsSheepTissue DistributionTransferrinUrinary BladderYeastsConceptsIGFBP-3IGFBP-3-induced apoptosisInsulin-like growth factorBladder smooth muscle cellsHuman liver complementary DNA libraryProstate cancer cellsSmooth muscle cellsImportant physiological effectsIGF actionBinding proteinProteins/receptorsMuscle cellsProtein 3Growth factorCancer cellsCell proliferationTF treatmentPhysiological effectsNegligible affinityHuman serum
1999
Cellular Actions of Insulin-Like Growth Factor Binding Proteins
Ferry R, Katz L, Grimberg A, Cohen P, Weinzimer S. Cellular Actions of Insulin-Like Growth Factor Binding Proteins. Hormone And Metabolic Research 1999, 31: 192-202. PMID: 10226802, PMCID: PMC4151550, DOI: 10.1055/s-2007-978719.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorFree insulin-like growth factorInsulin-like growth factor binding proteinGrowth factorCleavage of IGFBPsIGF-dependent actionsGrowth factor binding proteinFactor binding proteinPotent mitogenic agentsIGFBP proteasesIGF axisIGF receptorIGFBPsCellular actionsMitogenic agentsModulate levelsCellular proliferationCell growthBinding proteinSomatic growthHigh affinityProteinReceptors