2022
A Quality Improvement Bundle to Improve Outcomes in Extremely Preterm Infants in the First Week.
Travers C, Gentle S, Freeman A, Nichols K, Shukla V, Purvis D, Dolma K, Winter L, Ambalavanan N, Carlo W, Lal C. A Quality Improvement Bundle to Improve Outcomes in Extremely Preterm Infants in the First Week. Pediatrics 2022, 149 PMID: 35088085, PMCID: PMC9677934, DOI: 10.1542/peds.2020-037341.Peer-Reviewed Original ResearchConceptsSevere intracranial hemorrhageExtremely preterm infantsPreterm infantsIntracranial hemorrhageRates of acute kidney injuryMedian birth weightSpontaneous intestinal perforationDelayed cord clampingAcute kidney injuryQuality improvement initiativesBaseline rateGestational ageWeeks gestationCord clampingIndomethacin prophylaxisCongenital anomaliesIntestinal perforationBirth weightKidney injuryPrimary outcomeQuality improvement bundleInfantsFirst-weekBirthWeeks
2020
Early Skin-to-Skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial
Travers C, Ramani M, Gentle S, Schuyler A, Brown C, Dills M, Davis C, Mwenechanya M, Chomba E, Aban I, Manasyan A, Ambalavanan N, Carlo W. Early Skin-to-Skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial. The Journal Of Pediatrics 2020, 231: 55-60.e1. PMID: 33373672, DOI: 10.1016/j.jpeds.2020.12.064.Peer-Reviewed Original ResearchConceptsSkin-to-skin careResource-limited settingsEarly skin-to-skin careSequentially numbered sealed opaque envelopesSevere hypothermiaTertiary referral centerPhase 2 treatmentReferral centerNeonatal hypothermiaMaternal temperatureAdverse eventsAlone groupReduce hypothermiaBag groupInfantsHypothermiaClinical trial objectivesOpaque envelopesBirthSkin careTrial objectivesPhase 2CareHoursGroupOxygen saturation histograms predict nasal continuous positive airway pressure-weaning success in preterm infants
Gentle S, Ambalavanan N, Carlo W. Oxygen saturation histograms predict nasal continuous positive airway pressure-weaning success in preterm infants. Pediatric Research 2020, 88: 637-641. PMID: 31972856, PMCID: PMC7223394, DOI: 10.1038/s41390-020-0772-2.Peer-Reviewed Original ResearchConceptsPreterm infantsCPAP discontinuationOxygen saturationHigher oxygen saturationBackgroundContinuous positive airway pressureConclusionsIn preterm infantsPositive airway pressureCase-control studyWeeks gestationGestational ageAirway pressureControl infantsCPAP exposureBaseline characteristicsCPAPPostnatal weekClinical variablesPretermInfantsInclusion criteriaConsecutive daysGestationFiO2DaysWeaning