2024
Home is where the right ventricle lives: bronchopulmonary dysplasia-associated pulmonary hypertension and home ventilation
Gentle S, Ambalavanan N. Home is where the right ventricle lives: bronchopulmonary dysplasia-associated pulmonary hypertension and home ventilation. Pediatric Research 2024, 1-2. PMID: 39266628, DOI: 10.1038/s41390-024-03550-4.Peer-Reviewed Original ResearchAchieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants
Gentle S, Singh A, Travers C, Nakhmani A, Carlo W, Ambalavanan N. Achieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants. Archives Of Disease In Childhood 2024, 109: 941-947. PMID: 38937062, PMCID: PMC11503043, DOI: 10.1136/archdischild-2024-327014.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasia-associated pulmonary hypertensionOxygen saturation indexSurvival statusPreterm infantsPulmonary hypertensionHigher FiOLt;29 weeks' gestationFraction of inspired oxygenWeeks postmenstrual ageSingle-centre studyNon-invasive predictorCase-control studyPostmenstrual ageWeeks gestationBronchopulmonary dysplasiaRespiratory supportNon-survivorsInfantsOxygen saturationPatient outcomesPretermSurvivalHypertensionWeeksPredictors
2023
Interdependence in the Cardiorespiratory Network of Preterm Infants with Pulmonary Hypertension Using Mutual Information Analysis
Ramanand P, Indic P, Gentle S, Ambalavanan N. Interdependence in the Cardiorespiratory Network of Preterm Infants with Pulmonary Hypertension Using Mutual Information Analysis. 2016 Computing In Cardiology Conference (CinC) 2023, 50: 1-4. DOI: 10.22489/cinc.2023.354.Peer-Reviewed Original ResearchBronchopulmonary dysplasiaPreterm infantsPulmonary hypertensionCardiorespiratory networkComplications of PHHeart ratePH groupMechanisms of disease progressionRespiratory rateDisease progressionPretermInfantsOxygen saturationCardiorespiratory morbidityHypertensionGroupMean delayDysplasiaComplicationsMorbidityIntermittent Hypoxemia and Bronchopulmonary Dysplasia with Pulmonary Hypertension in Preterm Infants.
Gentle S, Travers C, Nakhmani A, Indic P, Carlo W, Ambalavanan N. Intermittent Hypoxemia and Bronchopulmonary Dysplasia with Pulmonary Hypertension in Preterm Infants. American Journal Of Respiratory And Critical Care Medicine 2023, 207: 899-907. PMID: 36449386, PMCID: PMC10111996, DOI: 10.1164/rccm.202203-0580oc.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasia-associated pulmonary hypertensionIntermittent hypoxemiaHypoxemic eventsReceiver operating characteristicPreterm infantsPulmonary hypertensionControl subjectsWeeks 6 daysExtremely preterm infantsWeeks 0 daysHigher risk of deathIdentification of infantsCase-control studyRisk of deathBronchopulmonary dysplasiaDesaturation frequencyEchocardiographic dataPostnatal dayBedside biomarkersIH eventsHigh riskInfantsHypoxemiaHypertensionLong duration433 Achieved oxygen saturations and risk for bronchopulmonary dysplasia-associated pulmonary hypertension in preterm infants
Gentle S, Singh A, Travers C, Nakhmani A, Carlo W, Ambalavanan N. 433 Achieved oxygen saturations and risk for bronchopulmonary dysplasia-associated pulmonary hypertension in preterm infants. The American Journal Of The Medical Sciences 2023, 365: s231-s232. DOI: 10.1016/s0002-9629(23)00440-8.Peer-Reviewed Original Research
2019
Oxygen Therapy and Pulmonary Hypertension in Preterm Infants
Gentle S, Abman S, Ambalavanan N. Oxygen Therapy and Pulmonary Hypertension in Preterm Infants. Clinics In Perinatology 2019, 46: 611-619. PMID: 31345551, DOI: 10.1016/j.clp.2019.05.009.Peer-Reviewed Original ResearchConceptsOxygen saturation targetsPulmonary hypertensionPreterm infantsSaturation targetsOxygen therapyHigher oxygen saturation targetsDevelopment of pulmonary hypertensionOptimal oxygen saturation targetsGoal of oxygen therapyEvaluating infantsCo-morbiditiesPretermHypertensionInfantsTherapyTrialsOutcomesNeOProMPrematurityHypoxemiaHyperoxemia