ATP Induces c-fos Expression in C6 Glioma Cells by Activation of P2Y Receptors
Zhang W, Turner D, Segura B, Cowles R, Mulholland M. ATP Induces c-fos Expression in C6 Glioma Cells by Activation of P2Y Receptors. Journal Of Surgical Research 2000, 94: 49-55. PMID: 11038302, DOI: 10.1006/jsre.2000.5984.Peer-Reviewed Original ResearchConceptsProtein kinase CType II protein kinaseMAP kinase kinasePhosphorylated MAP kinaseType I proteinC6 glioma cellsSecond messenger pathwaysExtracellular ATP functionsC-fos mRNA expressionKinase kinaseProtein kinaseGlioma cellsMAP kinasePhospholipase C inhibitorCalmodulin kinaseI proteinKinase CKinaseATP functionsMessenger pathwaysC inhibitorMRNA expressionCellular proliferationMultifactorial regulationC-fos expressionCholinergic intrapancreatic neurons induce Ca2+ signaling and early-response gene expression in pancreatic acinar cells
Turner D, Cowles R, Segura B, Romanchuk G, Barnhart D, Mulholland M. Cholinergic intrapancreatic neurons induce Ca2+ signaling and early-response gene expression in pancreatic acinar cells. Journal Of Gastrointestinal Surgery 2000, 4: 475-480. PMID: 11077322, DOI: 10.1016/s1091-255x(00)80089-x.Peer-Reviewed Original ResearchConceptsPancreatic acinar cellsC-fos expressionIntrapancreatic neuronsAcinar cellsEarly response gene expressionPancreatic exocrine functionIntracellular calcium levelsC-Fos proteinAR42J pancreatic acinar cellsExocrine functionCholinergic stimulationNeuronal depolarizationIntracellular calciumLong-term consequencesCalcium levelsNeuronal regulationNeuronsGene expressionPancreatic lobulesCalcium signalingCellsDepolarizationExpressionAverage increaseAgonists