2022
Isolated Terminal Ileitis in Children
Alper A, Bennett A, Rottmann D, Morotti R, Escalera S, Phatak U, Pashankar D. Isolated Terminal Ileitis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2022, 76: 338-342. PMID: 36729703, DOI: 10.1097/mpg.0000000000003679.Peer-Reviewed Original ResearchConceptsCrohn's diseaseTerminal ileitisAbnormal C-reactive protein levelsC-reactive protein levelsBowel wall thickeningLong-term outcomesRadiological evidenceRadiological featuresSevere inflammationPediatric literatureHigh prevalenceIleitisWall thickeningProtein levelsChildrenPrevalenceAdultsColonoscopyInflammationEndoscopicHistologicDiseaseMonths
2020
Pediatric unilobar resection in primary ciliary dyskinesia.
Sendon C, Cowles R, Worhunsky D, Hodson D, Morotti R, Bazzy-Asaad A, Esquibies A. Pediatric unilobar resection in primary ciliary dyskinesia. Minerva Pediatrica 2020, 74: 593-599. PMID: 32731729, DOI: 10.23736/s2724-5276.20.05802-8.Peer-Reviewed Original ResearchConceptsPrimary ciliary dyskinesiaSevere lung diseasePulmonary functionLung diseaseCiliary dyskinesiaAggressive medical managementSelective surgical removalQuality of lifeProgressive bronchiectasisUnilobar diseaseProphylactic antibioticsLung resectionAggressive administrationAirway clearanceMedical managementChronic bronchiectasisTherapy optionsLocalized bronchiectasisSurgical removalChronic infectionBronchiectasisRare caseAlternative treatmentNutritional statusNecrotic areas
2011
Progressive Familial Intrahepatic Cholestasis (PFIC) Type 1, 2, and 3: A Review of the Liver Pathology Findings
Morotti R, Suchy F, Magid M. Progressive Familial Intrahepatic Cholestasis (PFIC) Type 1, 2, and 3: A Review of the Liver Pathology Findings. Seminars In Liver Disease 2011, 31: 003-010. PMID: 21344347, DOI: 10.1055/s-0031-1272831.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphatasesATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 11ATP-Binding Cassette TransportersCholestasis, IntrahepaticDisease ProgressionGenetic Predisposition to DiseaseHeredityHumansLiverPhenotypePrognosisTerminology as TopicConceptsProgressive familial intrahepatic cholestasis type 1Intrahepatic cholestatic diseasesLiver pathology findingsCharacteristic pathologic featuresAutosomal recessive hereditary diseaseBile acid formationRecessive hereditary diseaseLiver histologyPathologic featuresHepatocellular originPathology findingsCholestatic diseaseDisease progressionFIC1 deficiencyMDR3 deficiencyBSEP deficiencyType 1DiseaseHereditary diseaseFirst descriptionDeficiencySpecific genotypesMolecular studiesCholestasisComplications
2009
Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient
Miloh T, Magid M, Iyer K, Kerkar N, Morotti R. Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient. Seminars In Liver Disease 2009, 29: 134-138. PMID: 19235665, DOI: 10.1055/s-0029-1202551.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlanine TransaminaseAntiviral AgentsAspartate AminotransferasesBiopsyChronic DiseaseEpstein-Barr Virus InfectionsGraft RejectionHepatolenticular DegenerationHumansImmunosuppressive AgentsLiverLiver TransplantationMaleReoperationTreatment OutcomeUp-RegulationVasculitisVenulesViral LoadConceptsCentral perivenulitisChronic rejectionLiver transplantationPolymerase chain reactionModerate acute cellular rejectionAcute cellular rejectionFulminant Wilson's diseaseAcute rejectionCellular rejectionEBV seroconversionImmunosuppressive treatmentLiver transaminasesLiver biopsyPediatric patientsAntiviral therapyCase reportNaive statusWilson's diseaseChain reactionTransplantationDiseaseWeeksSubsequent increaseRejectionImmunosuppression
2007
Hepatocellular Carcinoma and Congenital Absence of the Portal Vein in a Child Receiving Growth Hormone Therapy for Turner Syndrome
Morotti R, Killackey M, Shneider B, Repucci A, Emre S, Thung S. Hepatocellular Carcinoma and Congenital Absence of the Portal Vein in a Child Receiving Growth Hormone Therapy for Turner Syndrome. Seminars In Liver Disease 2007, 27: 427-431. PMID: 17979078, DOI: 10.1055/s-2007-991518.Peer-Reviewed Original ResearchConceptsFocal nodular hyperplasiaTurner syndrome patientsPortal veinNodular hyperplasiaSyndrome patientsHepatocellular carcinomaTurner syndromeGrowth hormone therapyRecombinant human growth hormoneHuman growth hormoneLiver transplantHormone therapyYounger patientsHepatic adenomaVascular anomaliesRelative riskCongenital absenceLiver lesionsGrowth hormonePatientsSyndromeCarcinomaHyperplasiaVeinTransplant
2006
Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis
Sinha J, Morotti R, Norton K, Gold D, Shneider B. Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis. Seminars In Liver Disease 2006, 26: 080-084. PMID: 16496236, DOI: 10.1055/s-2006-933566.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisWhite blood cell countMagnetic resonance cholangiogramMagnetic resonance cholangiopancreatographyHistory of hypothyroidismSclerosing cholangitisExtrahepatic biliary systemBiliary cirrhosisBile ductPortal tractsCystic fibrosisAlanine aminotransferaseAspartate aminotransferaseFatty pancreasMuscle antibodiesHepatic ductLiver diseasePathologic findingsPersistent elevationBiliary systemPercutaneous liver needle biopsyHepatitis B surface antigenHepatitis B surface antibodyAntinuclear antibody analysisAntismooth muscle antibodies
2001
Expression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia
Zhou H, Morotti R, Profitt S, Langston C, Wert S, Whitsett J, Greco M. Expression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia. Pediatric And Developmental Pathology 2001, 4: 364-371. PMID: 11441338, DOI: 10.1007/s10024001-0002-9.Peer-Reviewed Original ResearchConceptsClara cell secretory proteinPulmonary hypoplasiaWeeks gestational ageTranscription factor 1Thyroid transcription factor-1Cell-associated antigensSecretory proteinsTTF-1Surfactant proteinsHomeodomain transcription factorGestational ageFactor 1Distal lung developmentProximal-distal axisEpithelial gene expressionDistal lung parenchymaNormal fetal lungTranscription factorsFinal common pathwayLung organogenesisExpression patternsGene expressionImmunolocalization patternsProteinLung parenchymaLIVER PATHOLOGY IN CHILDREN WITH AIDS: A COMPARISON BETWEEN THE SOUTH AMERICAN AND NORTH AMERICAN POPULATION
Morotti R, Tata M, Drut R, Siminovich S, Menezes D, Guitierrez M, Kahn E. LIVER PATHOLOGY IN CHILDREN WITH AIDS: A COMPARISON BETWEEN THE SOUTH AMERICAN AND NORTH AMERICAN POPULATION. Fetal And Pediatric Pathology 2001, 20: 537-545. PMID: 11699578, DOI: 10.1080/pdp.20.6.537.545.Peer-Reviewed Original ResearchConceptsSA childrenGiant cell transformationTime of deathCases of childrenPeliosis hepatisCytomegalovirus infectionLymphoproliferative disordersOpportunistic infectionsHepatic changesPediatric hospitalLiver pathologyRapid progressionHigh prevalenceNA groupLiver tissueAIDSChildrenInfectionAmerican populationCell transformationNorth American populationsHepatisHistopathologicInflammationGroup
2000
Collision tumors in children: A review of the literature and presentation of a rare case of mesoblastic nephroma and neuroblastoma in an infant
Vegunta R, Morotti R, Shiels W, Rauck A, Besner G. Collision tumors in children: A review of the literature and presentation of a rare case of mesoblastic nephroma and neuroblastoma in an infant. Journal Of Pediatric Surgery 2000, 35: 1359-1361. PMID: 10999699, DOI: 10.1053/jpsu.2000.9334.Peer-Reviewed Original ResearchConceptsCollision tumorCongenital mesoblastic nephromaMesoblastic nephromaSynchronous primary malignant tumorsPrimary malignant tumorsRight kidneyMalignant tumorsRare caseSuch lesionsTumorsSynchronous occurrenceFirst reportNeuroblastomaInfantsNephromaAvailable literatureChildrenRare eventReportLesionsKidneyExpression of Thyroid Transcription Factor-1 in Congenital Cystic Adenomatoid Malformation of the Lung
Morotti R, Gutierrez M, Askin F, Profitt S, Wert S, Whitsett J, Greco M. Expression of Thyroid Transcription Factor-1 in Congenital Cystic Adenomatoid Malformation of the Lung. Pediatric And Developmental Pathology 2000, 3: 455-461. PMID: 10890930, DOI: 10.1007/s100240010092.Peer-Reviewed Original ResearchConceptsCongenital cystic adenomatoid malformationCCAM type 1TTF-1 expressionCystic adenomatoid malformationThyroid transcription factor-1Gestational ageTTF-1Type 1Adenomatoid malformationTranscription factor 1Fetal lungAlveolar cell markersBasal cellsEpithelial cellsWeeks gestational ageTTF-1 stainingType 4Factor 1Bronchiolar basal cellsDistal air spacesAlveolar type II cellsType I cellsEarly lung developmentType II cellsCCAM cases
1999
Demonstration of Communication between Alveolus and Interstitium in Persistent Interstitial Pulmonary Emphysema: Case Report
Yao J, Fasano M, Morotti R, Caprio M, Greco M. Demonstration of Communication between Alveolus and Interstitium in Persistent Interstitial Pulmonary Emphysema: Case Report. Pediatric And Developmental Pathology 1999, 2: 484-487. PMID: 10441627, DOI: 10.1007/s100249900153.Peer-Reviewed Original ResearchConceptsPersistent interstitial pulmonary emphysemaInterstitial pulmonary emphysemaPulmonary emphysemaHyaline membrane diseaseAirway ruptureUncommon complicationPremature infantsMechanical ventilationMembrane diseaseCase reportImmunohistochemical stainsAlveolar levelPresumed mechanismDiseaseAirway systemInterstitiumEmphysemaCongenital cystic adenomatoid malformation of the lung (CCAM): Evaluation of the cellular components
Morotti R, Cangiarella J, Gutierrez M, Jagirdar J, Askin F, Singh G, Profitt S, Wert S, Whitsett J, Greco M. Congenital cystic adenomatoid malformation of the lung (CCAM): Evaluation of the cellular components. Human Pathology 1999, 30: 618-625. PMID: 10374767, DOI: 10.1016/s0046-8177(99)90084-9.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, NeoplasmCD5 AntigensCystic Adenomatoid Malformation of Lung, CongenitalFetal DiseasesFetusGastrin-Releasing PeptideGlycoproteinsHumansHyaluronan ReceptorsNeoplasm ProteinsPeptidesProtein PrecursorsProteolipidsPulmonary Surfactant-Associated Protein CPulmonary SurfactantsSurface-Active AgentsConceptsCongenital cystic adenomatoid malformationCell-cell interactionsCystic adenomatoid malformationLung developmentCellular compositionAdenomatoid malformationProtein precursorCellular componentsNormal lung developmentPseudoglandular stageCCAM type 1Rare congenital lesionsSaccular stageNeuroendocrine cellsCell-associated antigensSurfactant proteinsEpithelial-lined cystsAdhesion moleculesCongenital lesionsCytodifferentiationImmunohistochemical stainsClara cellsFetal lungTracheobronchial treeMajor subtypes
1995
Invasive techniques for prenatal diagnosis: current concepts.
Bahado-Singh R, Morotti R, Pirhonen J, Copel J, Mahoney M. Invasive techniques for prenatal diagnosis: current concepts. Journal Of The Association For Academic Minority Physicians 1995, 6: 28-33. PMID: 7858373.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1994
Hyperechoic fetal bowel: The perinatal consequences
Bahado‐Singh R, Morotti R, Copel I, Mahoney M. Hyperechoic fetal bowel: The perinatal consequences. Prenatal Diagnosis 1994, 14: 981-987. PMID: 7899272, DOI: 10.1002/pd.1970141014.Peer-Reviewed Original ResearchConceptsCystic fibrosisFetal populationHyperechoic fetal bowelRate of complicationsIntrauterine growth retardationPerinatal consequencesFetal bowelFetal demiseAdverse outcomesBowel echogenicityHigh prevalencePrenatal sonogramsPriori riskGrowth retardationFibrosisWarrants investigationComplicationsChromosome abnormalitiesHigh rateFetusesRiskRisk figuresAneuploidyPopulationPrematurity
1991
The antenatal diagnosis of congenital heart disease using fetal echocardiography: is color flow mapping necessary?
Copel J, Morotti R, Hobbins J, Kleinman C. The antenatal diagnosis of congenital heart disease using fetal echocardiography: is color flow mapping necessary? Obstetrics And Gynecology 1991, 78: 1-8. PMID: 2047049.Peer-Reviewed Original Research
1990
Fetal hemolytic disease in a patient immunized by six antibodies: diagnosis and treatment.
Tantalo V, Rossi E, Gianotti G, Morotti R, Zuliani G, Buscaglia M, Galligani M. Fetal hemolytic disease in a patient immunized by six antibodies: diagnosis and treatment. Annali Di Ostetricia, Ginecologia, Medicina Perinatale 1990, 111: 321-5. PMID: 2092607.Peer-Reviewed Original ResearchConceptsFetal hemolytic diseaseSevere fetal anemiaSevere haemolytic diseaseFetal blood samplesFetal blood groupRare alloantibodyIntrauterine transfusionFetal anemiaMaternal antibodiesWeeks' gestationPregnant womenHaemolytic diseaseHemolytic diseaseCompatible donorsBlood samplesIndirect CoombsBlood groupAntibodiesDiseasePositive outcomesTransfusionAlloantibodiesPatientsPregnancyAnemiaTwin pregnancy with acephalic acardiac fetus. Anatomo-clinical description of 2 cases.
Sanchioni L, Presti C, Morotti R, Zuliani G, Kustermann A, Buscaglia M, Gandini S. Twin pregnancy with acephalic acardiac fetus. Anatomo-clinical description of 2 cases. Annali Di Ostetricia, Ginecologia, Medicina Perinatale 1990, 111: 174-80. PMID: 2275512.Peer-Reviewed Original ResearchConceptsAcardiac fetusTwin pregnanciesWeeks of gestationAnatomo-pathological findingsPlacental vascular anastomosesMultiple gestationsObstetric managementUltrasound scanRare malformationNormal fetusesVascular anastomosisSerial scansFetusesCardiac activityPregnancyGestationScansAnastomosisMalformationsCasesWeeks
1988
Ultrasound-guided fetal intravascular blood transfusion.
Zuliani G, Buscaglia M, Morotti R, Levi Setti P, Ghisomi L, Pardi G, Rossi E. Ultrasound-guided fetal intravascular blood transfusion. Annali Di Ostetricia, Ginecologia, Medicina Perinatale 1988, 109: 169-78. PMID: 3061352.Peer-Reviewed Original Research
1987
Intrauterine death of the fetus: causes and obstetric approach (case record at the L. Mangiagalli Obstetric and Gynecologic Clinic 1983-1986.
Zuliani G, Buscaglia M, Morotti R, Taglioretti A, Pardi G, Rossi E. Intrauterine death of the fetus: causes and obstetric approach (case record at the L. Mangiagalli Obstetric and Gynecologic Clinic 1983-1986. Annali Di Ostetricia, Ginecologia, Medicina Perinatale 1987, 108: 94-101. PMID: 3115169.Peer-Reviewed Original Research
1983
Hemolytic disease of the newborn due to rare alloantibodies
Zuliani G, Moroni G, Buscaglia M, Morotti R, Pardi G. Hemolytic disease of the newborn due to rare alloantibodies. International Journal Of Clinical And Laboratory Research 1983, 13: 449-457. PMID: 6419339, DOI: 10.1007/bf02906926.Peer-Reviewed Original Research