2006
Defects in E2F1/2 Expression Are Associated with Abnormalities in Cell Cycle and Differentiation in EKLF-Deficient Erythroid Cells.
Pilon A, Arcasoy M, Vayda S, Dressman H, Bieker J, Bodine D, Gallagher P. Defects in E2F1/2 Expression Are Associated with Abnormalities in Cell Cycle and Differentiation in EKLF-Deficient Erythroid Cells. Blood 2006, 108: 84. DOI: 10.1182/blood.v108.11.84.84.Peer-Reviewed Original ResearchHypersensitive sitesErythroid cellsMicroarray analysisCell cycleNumerous genesMature erythroblastsGel mobility shift assaysMicroarray dataFL cellsTranscription factor EKLFCell cycle controlMobility shift assaysΒ-globin expressionIngenuity Pathway AnalysisImmature erythroid cellsPrevious microarray analysisPrevious microarray dataE2F proteinsDefinitive erythropoiesisDNA replicationTranscription factorsColony forming assaysEKLFShift assaysTarget genes
2005
A Differentiation Block in Erythroid Cells Lacking Erythroid Krupple-Like Factor (EKLF).
Gallagher P, Arcasoy M, Vayda S, Dressman H, Bieker J, Bodine D. A Differentiation Block in Erythroid Cells Lacking Erythroid Krupple-Like Factor (EKLF). Blood 2005, 106: 526. DOI: 10.1182/blood.v106.11.526.526.Peer-Reviewed Original ResearchWild typeErythroid differentiationMicroarray analysisDifferentiation blockErythroid cellsFocus genesMouse Genome 430 2.0 ArrayAffymetrix GeneChip Mouse Genome 430 2.0 ArrayFetal liver cellsCell cycle defectsTerminal erythroid differentiationCell cycle controlFetal liverIngenuity Pathway AnalysisR2 cellsMature erythroid cellsΒ-globin geneErythroid progenitor cellsErythroid genesNumerous genesDefinitive erythropoiesisDNA replicationTranscription factorsΒ-spectrinBiological functions