Clinical features and metabolic complications for non-alcoholic fatty liver disease (NAFLD) in youth with obesity
Barbieri E, Santoro N, Umano G. Clinical features and metabolic complications for non-alcoholic fatty liver disease (NAFLD) in youth with obesity. Frontiers In Endocrinology 2023, 14: 1062341. PMID: 36733529, PMCID: PMC9887046, DOI: 10.3389/fendo.2023.1062341.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseInsulin resistancePediatric obesityDevelopment of NAFLDWhole-body insulin resistanceFatty liver diseaseType 2 diabetesAdipose tissue lipolysisCommon metabolic diseaseMetabolic complicationsClinical featuresLiver diseasePediatric populationTherapeutic optionsEctopic tissuePathophysiologic underpinningsTissue lipolysisRole of geneticsMetabolic diseasesObesityControl of insulinGrowth hormoneClinical implicationsDiseaseFatty acids