A Novel Sulfonylurea Receptor Family Member Expressed in the Embryonic Drosophila Dorsal Vessel and Tracheal System*
Nasonkin I, Alikasifoglu A, Ambrose C, Cahill P, Cheng M, Sarniak A, Egan M, Thomas P. A Novel Sulfonylurea Receptor Family Member Expressed in the Embryonic Drosophila Dorsal Vessel and Tracheal System*. Journal Of Biological Chemistry 1999, 274: 29420-29425. PMID: 10506204, DOI: 10.1074/jbc.274.41.29420.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsATP-Binding Cassette TransportersCloning, MolecularDrosophilaDrosophila ProteinsGene Expression Regulation, DevelopmentalGlyburideHumansIn Situ HybridizationMolecular Sequence DataOocytesPatch-Clamp TechniquesPhylogenyPotassium ChannelsPotassium Channels, Inwardly RectifyingReceptors, DrugRNA, MessengerSulfonylurea ReceptorsXenopus laevisConceptsDrosophila embryogenesisPotassium channel activityTracheal systemNovel Drosophila geneDrosophila dorsal vesselDorsal vesselABC transporter familyChannel activityReceptor family membersDrosophila genesGene duplicationPotassium channelsDrosophila systemTransporter familyGenetic approachesATP-sensitive potassium channel activityGenesFunctional studiesSulfonylurea receptorKir6.2 subunitEmbryogenesisATP-sensitive potassium channelsSURxSubunitsDistinctive sequenceCFTR Is a Conductance Regulator as well as a Chloride Channel
SCHWIEBERT E, BENOS D, EGAN M, STUTTS M, GUGGINO W. CFTR Is a Conductance Regulator as well as a Chloride Channel. Physiological Reviews 1999, 79: s145-s166. PMID: 9922379, DOI: 10.1152/physrev.1999.79.1.s145.Peer-Reviewed Original ResearchConceptsCystic fibrosis transmembrane conductance regulatorConductance regulatorABC transportersCassette transporter gene familyCFTR Cl- channel functionTransporter gene familyFamily of transportersChloride channelsFibrosis transmembrane conductance regulatorCl- channel functionABC transporter familyTransmembrane conductance regulatorIon channel proteinsCystic fibrosis epitheliaGene familyCellular functionsCellular proteinsTransporter familyChannel proteinsCF geneAmino acidsIon channelsRegulatorTransportersCl- channels